If You Have Diabetes, Your Risk of Alzheimer’s Increases Dramatically
Diabetes is linked to a 65 percent increased risk of developing Alzheimer’s, which may be due, in part, because insulin resistance and/or diabetes appear to accelerate the development of plaque in your brain, which is a hallmark of Alzheimer’s. Separate research has found that impaired insulin response was associated with a 30 percent higher risk of Alzheimer’s disease, and overall dementia and cognitive risks were associated with high fasting serum insulin, insulin resistance, impaired insulin secretion and glucose intolerance.
A drop in insulin production in your brain may contribute to the degeneration of your brain cells, mainly by depriving them of glucose, and studies have found that people with lower levels of insulin and insulin receptors in their brain often have Alzheimer’s disease (people with type 2 diabetes often wind up with low levels of insulin in their brains as well). As explained in New Scientist, which highlighted this latest research:
“What’s more, it encourages the process through which neurons change shape, make new connections and strengthen others. And it is important for the function and growth of blood vessels, which supply the brain with oxygen and glucose.
As a result, reducing the level of insulin in the brain can immediately impair cognition. Spatial memory, in particular, seems to suffer when you block insulin uptake in the hippocampus… Conversely, a boost of insulin seems to improve its functioning.
When people frequently gorge on fatty, sugary food, their insulin spikes repeatedly until it sticks at a high level. Muscle, liver and fat cells then stop responding to the hormone, meaning they don’t mop up glucose and fat in the blood. As a result, the pancreas desperately works overtime to make more insulin to control the glucose – and levels of the two molecules skyrocket.
The pancreas can’t keep up with the demand indefinitely, however, and as time passes people with type 2 diabetes often end up with abnormally low levels of insulin.”
Alzheimer’s Might be “Brain Diabetes”
It’s becoming increasingly clear that the same pathological process that leads to insulin resistance and type 2 diabetes may also hold true for your brain. As you over-indulge on sugar and grains, your brain becomes overwhelmed by the consistently high levels of insulin and eventually shuts down its insulin signaling, leading to impairments in your thinking and memory abilities, and eventually causing permanent brain damage.
Regularly consuming more than 25 grams of fructose per day will dramatically increase your risk of dementia and Alzheimer’s disease. Consuming too much fructose will inevitably wreak havoc on your body’s ability to regulate proper insulin levels.
Although fructose is relatively “low glycemic” on the front end, it reduces the affinity for insulin for its receptor leading to chronic insulin resistance and elevated blood sugar on the back end. So, while you may not notice a steep increase in blood sugar immediately following fructose consumption, it is likely changing your entire endocrine system’s ability to function properly behind the scenes.
Additionally, fructose has other modes of neurotoxicity, including causing damage to the circulatory system upon which the health of your nervous system depends, as well as profoundly changing your brain’s craving mechanism, often resulting in excessive hunger and subsequent consumption of additional empty carbohydrate-based calories.
In one study from UCLA, researchers found that rats fed a fructose-rich and omega-3 fat deficient diet (similar to what is consumed by many Americans) developed both insulin resistance and impaired brain function in just six weeks.
Plus, when your liver is busy processing fructose (which your liver turns into fat), it severely hampers its ability to make cholesterol, an essential building block of your brain crucial to its health. This is yet another important facet that explains how and why excessive fructose consumption is so detrimental to your health. Decreasing fructose intake is one of the most important moves you can take in decreasing the risk of Alzheimer’s disease in your lifetime.
At one time Alzheimer’s disease was a disease considered with unknown etiology or cause. Today it is considered different in the eyes of many in the medical profession. By Dr. Mercola, a physician who founded Mercola.com (Mercola.com is now the world’s top natural health resource site, with over 1.5 million subscribers.) feels this about Alzheimer’s disease: “The cause of the debilitating, and fatal, brain disease Alzheimer’s is conventionally said to be a mystery.
While we know that certain diseases, like type 2 diabetes, are definitively connected to the foods you eat, Alzheimer’s is generally thought to strike without warning or reason.
That is, until recently.
Now, a growing body of research suggests there may be a powerful connection between the foods you eat and your risk of Alzheimer’s disease and dementia, via similar pathways that cause type 2 diabetes. Some have even re-named Alzheimer’s as “type 3 diabetes.””
Can You Eat Your Way to Alzheimer’s?
In a recent animal study, researchers from Brown University in Providence, Rhode Island were able to induce many of the characteristic brain changes seen with Alzheimer’s disease (disorientation, confusion, inability to learn and remember) by interfering with insulin signaling in their brains.
Know that faulty insulin (and leptin, another hormone) signaling is an underlying cause for insulin resistance, which, of course, typically leads to type 2 diabetes. However, while insulin is usually associated with its role in keeping your blood sugar levels in a healthy range, it also plays a role in brain signaling. When researchers disrupted the proper signaling of insulin in the brain, it resulted in dementia.
What does this have to do with your diet? Let us go back to one of my articles on diabetes and how it impacts your diet. It states “The foods we eat that contain starches, carbohydrates, calories are made up of sugar. When food reaches our stomach in time digestion starts to take place where these foods are broken down in the stomach into individual or complex sugar molecules ( glucose being one of the most common and important ones). The glucose then passes from our stomach into our bloodstream when it reaches the liver 60 to 80 % of the glucose gets stored in that organ turning glucose into inactive glucose that’s converted to glycogen. The purpose for glycogen is when our glucose is low and our body needing energy we have this extra stored sugar, glycogen, to rely on. This is done by the liver which allows the sugar to be stored and released back into the bloodstream if we need it=energy, since nothing is in our stomach at that time, in that case scenario). When glucose=an active sugar, it is our energy for our cells and tissues and is a sugar ready to be utilized by the body where it is needed, by many organs. Think of a car for one moment, and what makes it run? That would be gas/fuel for it to function. The same principle with glucose in your bloodstream=fuel for the human body so we can function, for without it we wouldn’t survive. That is the problem with a person that has diabetes. They eat, they break the food down, the glucose gets in the blood but the glucose fuel can’t be used due to lack of or NO insulin at all. Insulin allows glucose to pass into our cells and tissues to be used as energy/fuel for the body parts to work. Glucose is used as the principle source of energy (It is used by the brain for energy, the muscles for both energy and some storage, liver for more glucose storage=that is where glucose is converted to glycogen, and even stored in fat tissue using it for triglyceride production). Glucose does get sent to other organs for more storage, as well. Insulin plays that vital role in allowing glucose to be distributed throughout the body. Without insulin the glucose has nowhere to go.”
So how does this impact your brain thinking? “This new focus on the Alzheimer’s/Diabetes/Insulin connection follows a growing recognition of insulin’s role in the brain. Until recently, the hormone was typecast as a regulator of blood sugar, giving the cue for muscles, liver and fat cells to extract sugar from the blood and either use it for energy or store it as fat. We now know that it is also a master multi-tasker: it helps neurons, particularly in the hippocampus and frontal lobe, take up glucose for energy, and it also regulates neurotransmitters, like acetylcholine, which are crucial for memory and learning.” What is effected with Alzheimer’s disease? Your memory and learning, So your diet plays a big role in Alzheimer’s disease.”
Over-consumption of sugars and grains is what ultimately causes your body to be incapable of “hearing” the proper signals from insulin and leptin, leaving you insulin resistant in both body and brain. Alzheimer’s disease was tentatively dubbed “type 3 diabetes” in early 2005 when researchers learned that the pancreas is not the only organ that produces insulin. Your brain also produces insulin, and this brain insulin is necessary for the survival of your brain cells. If your brain is incapable of hearing the proper signals causing the insulin and leptin in the brain making the organ insulin resistant=not doing its job for the brain tissue=brain cells die off=Diabetes 3 Alzheimer’s Disease. Than Learn in part 2 tomorrow how you can try to prevent this in your life with first discussing risks of Alzheimer’s increasing dramatically which is also known as Brain disease=diabetes 3.
“Diabetes may increase your risk of Alzheimer’s. Reduce this risk by controlling your blood sugar. Diet and exercise can help Ongoing research focuses on confirming the link between Alzheimer’s and diabetes and understanding why it exists. The link between type 2 diabetes and Alzheimer’s may occur as a result of the complex ways that type 2 diabetes affects the ability of the brain and other body tissues to use sugar (glucose) and respond to insulin. .”
Mayo Clinic states (is a not-for-profit medical practice and medical research group based in Rochester , Minnesota.)
So start by being good to your body & mind that will definitely impact your heart and soul in a positive way,
The heart is like the engine to a car but for us it’s the “pump” for the human body; without the engine the car won’t run and without the pump we won’t live. The normal size of the heart is about the size of your fist, maybe a little bigger. It pumps blood continuously through your entire circulatory system. The heart consists of four chambers, 2 on the right and 2 on the left. The right side only pumps high carbon dioxide levels of blood, after all the oxygen was used by the tissues and returns to the heart in the right upper chamber and leaves to the lung from the right lower chamber. From the lungs it than goes to the left side of the heart now, which is a very short distance as opposed to where the left side pumps the blood. The L side of the heart pumps blood to the feet, brain and all tissues in between with high oxygen levels of blood. This is why the L side of the heart does more work than the R side since the blood leaving the L side has a longer distance in distributing oxygen. The heart pumps the blood with high oxygen blood levels to reach all your tissues and cells, going to the feet, brain, and to all other tissues in between returning home again to the right side of the heart (upper chamber) to get sent to the lungs again for more oxygen. This is why the muscle on the L side of the heart is larger than the right, it works harder. Every time your heart beats (the sound we call lub dub) the organ is sending out a cardiac output of blood either to the lungs for more oxygen or to the body tissues through the aorta to give oxygenated blood to your tissues and cells. This is the mechanics of how the heart works in our body.
Let’s see what can occur if the heart doesn’t function properly. If your heart is not pumping out a sufficient amount in your cardiac output to either the lungs (from rt. Side) or to the tissues (from the lt. side) than it tries to work harder where it does ok at first but over time weakens. As this weak heart struggles to pump blood the muscle fibers of the heart stretch. Over time, this stretching leaves the heart with larger, weaker chambers. The heart enlarges (cardiomegaly). If this continues to go on this could go into R or L sided heart failure. When this happens, blood that should be pumped out of the heart backs up in the lungs (L sided failure) or in the tissues (R sided failure). The side the failure is on doesn’t allow proper filling of the chambers on that side and back up happens; so if on the L the fluids back up in the lungs or the R the fluids first back up in the veins which can expand to hold extra blood but at some point dump the extra fluids in your tissues (This is edema in feet first due to gravity). This is all due to overloading of the blood not filling up in the chambers of the heart to make a good cardiac output of blood and in time the fluid backs up (bad pumping=backup of blood=fluid overload in the lungs (pulmonary congestion) to fluid staying in the skin (first the lower extremities due to gravity=feet which we call edema working its way up the legs.). This condition in time with no treatment will go into congestive heart failure (CHF) to the other side of the heart if not controlled. CHF can range from mild to severe. There is 670,000 cases are diagnosed with this every year and is the leading cause of hospitalization in people over 65 y/o. Causes of CHF are: heart attack, CAD (coronary artery disease), cardiomyopathy, conditions that overwork the heart like high blood pressure, diabetes and obesity (These diseases can be completely preventable or at least well controlled).
There is many of us in this world with knowing how our activity/exercise, eating, and habits could be better for health but do little action if any on our own to change it, which is a large part for certain diseases being so high in America (diabetes, stroke, cardiac diseases=high blood pressure, atherosclerosis, arteriosclerosis to CHF and more). If people were more healthier and more active regarding these diseases alone it would decrease in population creating a positive impact on how our health system with insurance presently (a disaster) with our economy for many could get better. A healthy heart can pump to all parts of the body in a few seconds which is good cardiac output from the organ but when it gets hard for the heart to keep up with its regular routine it first compensates to eventually it decompensates causing ischemia (lack of oxygen to the heart tissue). It’s like any tissue in the body, lack of oxygen=lack of nutrients to the body tissue=STARVATION and with lack of oxygen will come PAIN eventually to death if not treated. Take the heart, if it isn’t getting enough oxygen it can go into angina. That is reversible since it is heart pain due to not enough oxygen to the heart tissue=no damage but if left untreated what will occur is a heart attack=myocardial infarction (MI) and is permanent damage because scarring to the heart tissue takes place.
Let’s understand what the heart can develop over time with an unhealthy heart due to bad health habits. If you are eating too much for too long foods high in sodium your vessels will narrow in size. By allowing this you increase the pressure in the vessels that increases your blood pressure called hypertension. If you are also inactive you are at risk of obesity which puts stress on the heart and in time causing high B/P. Constantly be in a high B/P and this could cause the vessel to rupture (at the heart=possible heart attack, at the brain=possible stroke, also called CVA with both on high occurrences in our population of the US.). With bad habits (especially poor diet, inactive, and smoking) you can cause over time atherosclerosis=a blockage in the artery with the resolution surgery (from a cardiac catheterization up your groin or having difficulty in the arm to the heart where an angiogram to an angioplasty with possibly a stent is performed or if the blockage to blockages is so bad a CABG=coronary artery bypass=a 6hr plus operation where diversion of a vein from your leg (donor graft site) around the blockage is done. Smoking can lead to this but it also can cause your vessels to become brittle=arteriosclerosis. Healthy Habits would impact a positive result for all people who have had this diagnosis before but most important be a great PREVENTATIVE measure for people not diagnosed with cardiac disease. There are 4 things you have no control over heredity, age, sex, and race but healthy habits are sure to benefit you by keeping the odds down of you inheriting, help your age factor, and race a lot can be associated with eating cultural habits.
If you make the decision to live a life that’s healthy for your heart through proper eating, doing healthy habits and doing some exercise or activity with balancing rest in your busy schedule and would like direction or want to expand your diet/exercise/healthy habits then you came to the right blog. Go to my website for no fee, no charge, no hacking, just letting you check us out to look further in understanding how to take a healthier shape for your life with Dr. Anderson and even myself as your health coach in helping you learn what healthier habits or changes you feel you need and want for a healthier way of living. It allows you to make all the decisions in what you want to do regarding your health. Includes what to eat (diet), what exercise/activity, and what healthy habits you want to add in your life. We just provide the information and healthy foods in your diet through information to broaden your knowledge even a catalog on diet foods, if you so choose to do so. You make all the choices. Wouldn’t you want less heart disease or obesity or diabetes for yourself and for others throughout the nation including the future generations? Than join me and others. Thank you for taking the time to read my article in how we can help you with others gets healthier you including a healthier USA. Click onto heathyusa.tsfl.com and I hope to hear from you soon. If you like what you see spread the good cheer. Let’s build a stronger foundation regarding HEALTH in America.
“I’d rather see you drink a glass of wine than a glass of milk. So many people drink Coca-Cola and all these soft drinks with sugar. Some of these drinks have 8 or 9 teaspoons of sugar in them What’s the good of living if you can’t have the things that give a little enjoyment?”
Jack LaLanne
Enzymes are vital for processes to take place in our body without them they couldn’t take place. What are enzymes exactly? We have an many enzymes in our body from our saliva to our pancrease. Enzymes are specialized proteins that are produced by living cells to catalyze reactions in the body=breakdown. Protein in the form of an enzyme acts as a catalyst. A catalyst in action brakes down something, any chemical substance affected with the speed of reaction without being permanently altered by the reaction. For a chemical or biochemical reaction to occur, a certain amount of energy is required=the activation energy. Energy can be transformed from one state to another. The role of an enzyme is to decrease the amount of energy needed to start the reaction. Exactly how enzymes lower activation energies is not completely and fully understood but it is known that an enzyme attaches itself to one of the reacting molecules, this is called a substrate complex. Thousands of enzymes exist but each kind can attach ONLY to one kind of substrate. The enzyme molecule must fit exactly with the substrate molecule (just like how pieces in a jigsaw puzzle have to fit in their specific space of the picture). Well, if the substrate and enzyme don’t perfectly match or fit properly no reaction takes place. When they do fit perfectly the substrate molecule can react with other molecules in a synthesis reaction and when completed the enzyme is free to move on elsewhere to connect with another substrate molecule. This whole process takes place quickly. Clearly, enzymes are essential to the body’s overall homeostasis. (In order to lead a healthy life, we need to bring a balance in the way we lead our lifestyle. Homeostasis is nothing but a mechanism which helps the human body maintain a balance between the internal and external environment). Enzymes quickly perform catalyze chemical reactions and they also govern the reactions that occur. Enzymes are named by adding the suffix “ase” to the name of their substrates. For example there is: The breaking down of starches = the enzyme that does this function is amylase. (Know this about amylase, it is present in human saliva where it begins the chemical process of digestion; that starts in our mouth. Foods that contain much starch but little sugar, such as rice and potato, taste slightly sweet as they are chewed because amylase turns some of their starch into sugar in the mouth. The pancreas also makes amylase (alpha amylase) to hydrolyse dietary starch into disaccharides and trisaccharides which are converted by other enzymes to glucose to supply the body with energy. There is even b and y amylases. Ending product on enzymes breaking down starches or carbohydrates gives us one thing only sugar.)
The breaking down of sugars, like sucrose = the enzyme is sucrase. The ending product of the enzyme is it breaks down complex sugars to more simple sugars in the body.
The breaking down of fats (lipids) = the enzyme is lipase. Lipase perform essential roles in the digestion, transport and processing of dietary lipids in most if not all living organisms (example (triglycerides, fats, oils).Most lipases act at a specific position on glycerol backbone of lipid substrate (A1,A2 or A3 in the small intestines). For example, human pancreatic lipase (HPL) is the main enzyme that breaks down dietary fats in the digestive system, converts triglyceride substrates found in ingested oils to monoglycerides and two fatty acids. Know that glycerol is a simple sugar compound. Enzymes deal with breaking down our foods because they take a major role in what we call the process digestion in the human body but notice what the ending result is of mostly every ingredient out of 3 of our food groups, which is SUGAR. It’s because of the food already having some sugar in it but more importantly also the chemical reaction with the enzyme to allow the food to break down into smaller compounds to be utilized in the body=simpler sugar compounds which also plays a part in the entire digestion process.
How do we deal with this to prevent obesity? Do what I did go on a 6 small meal diet. Eat a meal every 3 hours with keeping fat, calories/sugar, carbohydrates in proper proportions to prevent excess sugar in the meals to not allow fat storage=weight gain. Of course some exercise or activity daily or every other day helps tone the muscle and not let it flab due to cellulite. Live healthier habits of living not a month, 3 months or 6 months but make it your daily routine with treating yourself to foods you don’t eat daily to maintain a good weight and increase your health status to allow you to live a happier, longer and more exciting life. Dr. Anderson with his book “Dr. A’s Habits of Health” with me as your medifast coach show you how easy it is. You learn all 4 food groups and how to divide them up in your meals with first starting with medifast foods 3 to 6 months and when you feel you have reached the weight you want to be at with knowing the routine you can stop or continue with regular foods and medifast for snacks only, maybe. You make all the choices.
Let’s not forget with enzymes they also break proteins down in our body. The breaking down of proteins=Trypsin Proteins that are large biological molecules consisting of one or more chains of amino acids. Proteins perform a vast array of functions within living organisms, including catalyzing metabolic reactions, replicating DNA, responding to stimuli, and transporting molecules from one location to another. Trypsin is a enzyme catalyst, which allows the catalysis of chemical reactions. The ending product of the break down is amino acids not sugar. Know high on a protein diet continuously for years can hurt the body also.
Enzymes deal with breaking down our foods because they take a major role in what we call the process digestion in the human body. but notice what the ending result is of mostly every ingredient in our 4 food groups is; SUGAR. It because of the food has some sugar in it but also the chemical reaction with the enzyme to allow the food to break down into smaller compounds to be utilized in the body with send through the entire digestion process.
There are risks with eating just high protein diets for long periods of time. You put yourself at risk for: Osteoporosis: Research shows that women who eat high protein diets based on meat have a higher rate of bone density loss than those who don’t. Women who eat meat lose an average of 35% of their bone density by age 65, while women who don’t eat meat lose an average of 18%. In the long run, bone density loss leads to osteoporosis.
However, the risks of using a high-protein diet with carbohydrate restriction for the long term are still being studied. Several health problems may result if a high-protein diet is followed for an extended time:
If you want to follow a high-protein diet, do so only as a short-term weight-loss aid. Also, choose your protein wisely. Good choices include fish, skinless chicken, lean beef, pork and low-fat dairy products. Choose carbs that are high in fiber, such as whole grains and nutrient-dense vegetables and fruit.
It’s always a good idea to talk with your doctor before starting a weight-loss diet. And that’s especially important in this case if you have kidney disease, diabetes or other chronic health condition.
So if you want to continue on high protein diets longer than 6 months know how to alkalize the body chemicals to decrease the proteins and there are supplements that can do that via the pharmacy or look up even online.
If you’re interested with wanting Dr. Anderson and myself in getting you started go to heathyusa.tsfl.com and just take a peek at no charge, no hacking, no donations, no subscription just letting you know what we offer; you may just like what you see. I did it and lost 22lbs. I feel better and healthier. You may just pass it over to family and friends spreading the good news that could just make our country a healthier one.