Archive | March 2015

PART I What is Epilepsy with a etiology; metabolic or systemic cause.

Most people with epilepsy are otherwise healthy; as long as it is controlled like most other diseases.  A seizure is a physical manifestation of paroxysmal and abnormal electrical firing of neurons in the brain.  Think of it as numerous voltage (hyperexcitability of neurons) going throughout the brain meaning brain waves going in all directions with the brain saying its too much activity.  In simpler terms the brain is saying I don’t know what to do, too much brain wave excitability for the organ to register in what to do and freaks out causing the brain to go into a seizure.

When the seizure occurs there is a decrease in oxygen since the brain isn’t capable to send messages during the seizure.  If the seizure continues to repeat one right after another the person is in status epilepticus and if the seizures do not stop the person can lead to a neuronal death;  like John Travolta’s son who died of this for example.

The term seizure disorder may refer to any number of conditions that result  in such a paroxysmal electrical discharge.  These conditions could be metabolic or structural in nature.

For example, if metabolic this could be “Canavan disease” which is primarily a disease of demyelination.  Your myelin sheath that protects and insulates the nerves is being destroyed and can cause a seizure as one of the symptoms.

*Another example being metabolic is thought to be caused by brain acetate deficiency resulting from a defect of Nacetylaspartic acid (NAA) catabolism (meaning breakdown is occurring).  Accumulation of NAA, a compound thought to be responsible for maintaining cerebral fluid balance, can lead to cerebral edema and neurological injury, like a seizure as one symptoms of the disease.

*A structural condition to cause a seizure could be a tumor in the brain.  Than there is just idiopathic, unknown cause for the epilepsy which if starts in childhood can resolve by the child growing out it, like in petite mal seizures but it not it goes into motor/focal or grand mal that is permanent the individual needs Rx for life.

Remember, etiology (the cause) of Epilepsy can be generally a sign of underlying pathology involving the brain–knowing the cause.  To find this out diagnostic tooling be a neurologist who specializes in epilepsy is the best resource to go to.  The epilepsy may be the first sign of a nervous system disease (ex. Brain tumor), or it may be a sign of a systemic or metabolic derangement.  Where the treatment may be able to resolve the seizure symptom completely where this wasn’t a seizure disorder or epilepsy but just a symptom due to another disorder that may be 100% cured, like a operable tumor removed surgically from the brain.

Metabolic and Systemic Causes of Seizures:

a.) Electrolyte Imbalance=In the blood having acidosis, heavy metal poisoning, Hypocalcemia (low Ca+) , Hypocapnea (low carbon dioxide), Hypoglycemia (low glucose), Hypoxia (low oxygen), Sodium-Potassium imbalance, and than Systemic  diseases (liver, renal failure, etc…).  Then their is also toxemia of pregnancy, and water intoxication.

b.) Infections like meningitis, encephalitis, brain abcess.

c.) Withdrawal of sedative-hypnotic drugs=Alcohol, Antiepileptic drugs, Barbiturates, Benzodiazepines.

d.) Iatrogenic drug overdose=Theopylline, Penicillin.

Other causes of epilepsy can be Trauma, Heredity.

Structural causes of epilepsy:

Head trauma/Degenerative Disease like Alzheimer’s or Creutfeldz-Jacob or Huntington’s Chorea or Multiple Sclerosis or Pick’s Disease. There is also tumors or genetic disease or Stroke or Infections or Febrile seizures.

 

Differences between tumors.

Differences between tumors are as follows:

Benign Tumors ones are the following:

Encapsulating (the big answer to resolution of a tumor like this is this a tumor that is surgical to remove or can radiation or chemo decrease the size of it to nothing).

Non metastasizing-meaning it hasn’t spread anywhere.

Well – Differentiated-meaning easy to detect.

Slow – growing (just what is says)

Malignant Tumors ones are the following:

Invasive,Metastasizing,FrequentlyUndifferentiated,OftenRapidGrowing.

Know that carcinogenesis is the process of inducing a malignant tumor in an animal or human. Much of the research in carcinogenesis resolves around deoxyribonucleic acid (DNA), the influence of carcinogens on DNA, and the genes that are involved in differentiation (of this growth vs normal tissue of the body) and control of cancerous cell growth.

There is viral and chemical carcinogenesis.   Both RNA and DNA viruses have been identified as causing natural and experimental tumors. Research has shown herpes viruses are DNA viruses. For almost every herpes group there is some experimental or epidemiological evidence linking it to human malignancy. Example Epstein-Barr viruse has been associated with Burkitt’s Lymphoma in West African children and nasopharyngeal cancer among Asian populations. Herpes simplex virus-1 has been linked to oral cancer and herpes simplex virus-2 to cervical cancer. All herpes viruses share a characteristic ability to remain latent within the body over long periods. Although they may be found throughout the body, CMV (cytomegaloviruse) infections are frequently associated with the salivary glands in humans and other mammals. Other CMV viruses are found in several mammal species, but species isolated from animals differ from HCMV in terms of genomic structure, and have not been reported to cause human disease.

The RNA viruses, also called oncoviruses or retroviruses induce leukemia, lymphoma, and mammary tumors in animals. To complete their natural cycle, these viruses must manufacture a viral DNA that is then integrated into the host cell DNA. To do this they produce an enzyme and the enzyme is able to use RNA as a template to produce DNA. Since these viruses can remain latent in a cell for long periods of time, it is only by identifying the enzyme or the viral DNA that scientists are able to detect cells infected with these viruses. This enzyme has been identified in some human leukemia and lymphoma cells.

In addition, approximately 20 oncogenes have been identified with these RNA viruses and some of these oncogenes have also been detected in human bladder cancer cells, Burkitt’s lymphoma, and promyelocytic leukemia.

There is also radiation carginogenesis. There is external radiation; take Leukemia which was the first cancer related to radiation exposure that was seen in the atomic bomb survivors. Within 6-8 years after the bomb, the incidence rates of leukemia increased to levels well above those seen in the Japanese population who were not exposed. The peak was highest from 1950 to 1952, at which time the incidence was 116:100,000, as compared with 3-4:100,000 to the unexposed population.

Internal Emitters – One of the most famous classics is that of the luminescent instrument – dial painters. The paint was used to create luminescent faces on watches and clocks containing radium. While painting, the workers licked the brushes and thus ingested the radium. Radium, when ingested is deposited in bone and tends to remain there.) Among this group, bone cancer or osteogenic sarcoma, a rare tumor, became prevalent. With this type of knowledge it led to limitations on surface testing of atomic weapons. Atomic weapons contain radioactive compounds that can become deposited in the bone.

Ultraviolet radiation or the Sunlight – One of the most obiquitous forms of radiation that every person is exposed to is the sunlight. Ultraviolet rays do not penetrate deeply. Most statistics on cancer do not include skin cancer due to it being treatable (the easiest cancer to treat on average). Another more dangerous type of cancer is melanoma that has been linked to sunlight exposure.

Tumor classification shows because the study of tissues originates with the study of their development in the embryo, the class of the tumor is often based on the tissues from which the tumor is derived.

Grading the cancer, besides classifying the tumor according to the tissue origin the pathologist will classify it looking at other characteris- tics. This aspect is Grading the cancer from level 1 or 2 or 3 or 4. If cells of classification in the tumor look like the mature cells of the tissue than the tumor is well differentiated=Grade 1. This type of tumor generally has a better prognosis compared to a tumor that is poorly differentiated or does not resemble the tissue from which it originated. Sometimes a poorly differentiated tumor is called anaplastic. An anaplastic tumor would have the highest grade of 4. Remember even though tow tumors might be similarly classified and have identical grades, in two different individuals the tumors might act differently. Because each patient is unique, has a different history, different immune responses, and different reserves, similar tumors might act very differently.

DIAGNOSIS

A definitive diagnosis of cancer can only be made after an examination of tissue obtained from a surgical procedure or biopsy. Biopsies can be excisional, meaning the whole lesion is removed, or incisional in which only part of the presumptive tumor is removed. Specimens can also be obtained from a needle biopsy. In this a core of tissue is drawn up in a needle.   Cytological examination of exfoliated cells, as done in a pap smear, can lead to a presumptive diagnosis of cancer but often a surgical biopsy will be performed to confirm the diagnosis. Often the patient undergoes many other diagnostic tooling procedures besides the biopsy in the attempt to determine the nature and extent of the illness=from blood tests, diagnostic x-ray studies, and endoscopic procedures. These tests with the biopsy done are used to evaluate the extent of the disease in the patient. This process of determining the extent of tumor in an individual is called staging.

Treatment

Cancer treatment can be surgery, chemo or radiation or even all 3.

QUOTE FOR WEDNESDAY:

“About half of all men and one-third of all women in the US will develop cancer during their lifetimes. Today, millions of people are living with cancer or have had cancer.  The risk of developing many types of cancer can be reduced by changes in a person’s lifestyle, for example, by staying away from tobacco, limiting time in the sun, being physically active, and eating healthy.”

AMERICAN CANCER SOCIETY

What is Cancer?

Cancer can be a simple disease or a monster to the body and let us first start reviewing the basics of cancer to understand this sentence. 

The body is made up of trillions of living cells.  Normal body cells grow, divide to make new cells, and die in an orderly fashion.  During the early years of a person’s life, normal cells divide faster to allow the person to grow. 

After the person becomes an adult, most cells divide only to replace worn-out or dying cells or to repair injuries. 

The pathophysiological responses of a patient with cancer are frequently determined by the size and extent of the tumor and by the presence or absence of metastases.

Cancer starts when cells in a part of the body start to grow out of control. Cancer cell growth is different from normal cell growth. Instead of dying, cancer cells continue to grow and form new, abnormal cells. Cancer cells can also invade (grow into) other tissues, something that normal cells cannot do. Growing out of control and invading other tissues are what makes a cell a cancer cell. Cells become cancer cells because of DNA (deoxyribonucleic acid) damage.

DNA is in every cell and it directs all its actions. In a normal cell, when DNA is damaged the cell either repairs the damage or the cell dies. In cancer cells, the damaged DNA is not repaired, but the cell doesn’t die like it should. Instead, the cell goes on making new cells that the body doesn’t need. These new cells all have the same damaged DNA as the first abnormal cell does=cancer cells.

The normal cells of a human body=Our red blood cells (our iron and cells that provide nutrition to our tissues by feeding oxygen to all our tissues), our white blood cells (fight infection off our body-part of immunity system), and our platelets (controls our clotting of the blood) all are taken over by the cancer cells especially if the cancer is primarily in the bone or metastasized to the bone since this organ in the human body produces all our blood cells in the bone marrow and the cancer in that causes the bone marrow to make cancer cells which is hard to cure especially if your cancer in the bone is at grade 3 or 4.   If a patient’s cancer is grade 1 or 2 its much easier to treat to possible completely cure. 

Again cancer can be a simple disease or a monster.

People can inherit abnormal DNA (it’s passed on from their parents), but most often the DNA damage is caused by mistakes that happen while the normal cell is reproducing or by something in the environment. Sometimes the cause of the DNA damage may be something obvious like cigarette smoking or sun exposure. But it’s rare to know exactly what caused any one person’s cancer. In most cases, the cancer cells form a tumor.

Some cancers, like leukemia, rarely form tumors. Instead, these cancer cells involve the blood and blood-forming organs and circulate through other tissues where they grow. Neoplasms or “new growths” are relatively autonomous (independent).  This means that the growth and its behavior are more or less independent of the host (the normal body functions).

  Neoplasms have been defined as benign or malignant; cancer is a common synonym used to refer to a malignant neoplasm.  The difference between a benign and malignant neoplasm depends on its behavior in the host.  Now if the neoplasm stays localized, enlarges slowly, is homogeneous in appearance, and can be resected or removed, then it is benign. 

On the other hand, if the neoplasm spreads or metastasizes to other areas of the body, infiltrates and causes the destruction of normal tissue, left untreated, will kill the host, then the neoplasm is considered malignant (it takes over in the body).

If a large tumor is occupying the oral cavity, then the patients will have problems with ingestion that might lead to an altered immune-responsiveness. 

If the tumor is in the large colon, then obstruction of the lumen, changes in bowel habits, and GI bleeding can occur. 

In addition, if tumors are large they often outgrow the blood supply, which leads to necrosis and bleeding. 

However, all the above changes are relatively late signs; the tumor would be quite large for a patient to exhibit these effects.  Most small tumors are painless and symptomless. 

In one sense this is unfortunate.  If small tumors were painful, perhaps more patients would seek earlier treatment and tumors could be treated more successful being diagnosed before they are large.

 

QUOTE FOR TUESDAY:

The biggest challenge in raising children today, according to parents and non-parents alike, is dealing with the outside influences of society. Nearly four-in-ten Americans (38%) list societal factors when asked in an open-ended format to name the biggest challenge for parents today. Among the top specific concerns mentioned are drugs and alcohol, peer pressure, and the impact of television and other media.

http://www.people-press.org/2007/05/02/motherhood-today-tougher-challenges-less-success/

 

 

Why disciplining your kids plays a significant role in how the child will turn out as a responsible person in adulthood!

 As a parent, you serve many roles. You are the caregiver and the nurturer, and you want to be the friend. From time to time, however, you also have to be the disciplinarian, teaching your children right from wrong and helping guide them toward appropriate behaviors and smart decisions. Understanding why discipline is important for your children will help you implement effective disciplinary techniques that make for happy and well-behaved children turning them out to high probability of an effective grown up in the adult world.  Your childhood builds the FOUNDATION of how you will turn out as an adult.  Be with no limitations, living 100% politically correct, no rules or regulations, teaching your child everyone wins and no one ever loses expect a lot of disarray for that youth when the reach adulthood.  For example be a parent who doesn’t  discipline, does everything politically correct raising the child which in this case compared to an adult the child has not earned the years of experience to even think like an adult yet.  At the same time the child has not produced anything in having the capability to act like an adult yet  that’s why they are called children with the parents their for mentorship or guidance.

Look at what this type of thinking in not disciplining your child either verbally or physically with a single spanking has done to our society (not beating the crap out of the child, for any individual being dramatic thinking I may mean that and I don’t).  Our own kind are children and young adults you hurt each other both mentally and physically.

There are many reasons why a parent may not want to discipline a child. Some parents may be reluctant to discipline children because they want to avoid having conflict or because they don’t want to have their child be angry at them. Others may be unable or unwilling to devote time and energy to the task of disciplining children. And still others may have unpleasant memories of being disciplined when they were children, and may want to make things easier on their own kids by relaxing rules and giving them more free rein.

But the fact is, discipline is not about creating conflict with your child or lashing out in anger. Child discipline, when done correctly, is not about trying to control your child but about showing her how to control her own behavior. It is not about punishing a child for doing something wrong but about setting clear parameters and consequences for breaking rules so that she learns how to discipline herself.

A child who has been taught right from wrong and has a solid sense of what is negative and positive behavior will know when she has done something wrong. She will want to behave correctly out of a desire to be a good citizen and a member of her family and society — not because she fears punishment.

 What disciplining your children is and can do:

-Teaching Responsibility

Discipline teaches your children to be responsible for their actions. A common form of discipline is teaching children to experience the consequences of their decisions. If you warn your daughter that failing to pick up her toys will result in loss of dessert, for example, and she does not pick up her toys, she will experience the consequences of her decision. When you discipline children using this consequences model, you help them learn how to be responsible for their actions and, thus, control the consequences they experience.

-Instilling Appropriate Behavior

Discipline teaches your children proper behavior in a variety of circumstances. When you discipline your child for poor behavior, he learns about what behavior is acceptable. According to an article in the journal Paediatrics and Child Health, discipline can foster appropriate behavior in children, teaching them how to interact with others, when to postpone pleasure and how to tolerate discomfort. Thus, discipline can help you create better-behaved children who are respectful of others.

-Establishing Self-discipline

Effective disciplinary techniques can minimize your role as the disciplinarian in the future. As your child learns what behaviors, actions and words are acceptable and unacceptable, she will acquire self-discipline skills. After learning of the negative consequences of bad behavior, your child may avoid that behavior in the future to avoid punishment. Thus, parental discipline can foster healthy self-discipline in children, which can improve their behavior.

-Building Confidence

Positive discipline can build your child’s confidence as well. Well-disciplined children often display appropriate behaviors and make smart decisions in difficult situations. Strong decision-making abilities and appropriate behavior can help build your child’s confidence. As the Purdue Extension website explains, one of the goals of discipline is to raise confident and responsible children, so your discipline can positively impact your child’s confidence for the long term.

Why It’s Important to Discipline Children

What many parents who are reluctant to discipline children may not understand is how damaging it can be for a child to lack boundaries. Without discipline, children will be deficient in the following important life skills.

-They will lack self control.

-They will not respect their parents or other authority figures.

-They will not know what is appropriate behavior.

-They will be willful, selfish, and generally unpleasant company.

-They will not have social skills that are important for making friends such as empathy, patience, and knowing how to share.

-They will be more likely to engage in negative behaviors that are harmful and even potentially dangerous for themselves as well as others.

-They will be unhappy.

Traits of Children Who Have Been Disciplined

On the other hand, children who have been given firm but loving guidance have the following traits and abilities:

  • They have more self control and are more self-sufficient.
  • They are more responsible and enjoy “being good” and helping others at home, at school and in the world at large.
  • They are more self-confident. They know their opinions and feelings will be heard, and that their parents love them even when they make mistakes.
  • They know that they are accountable for their mistakes or misbehavior, and are more likely to make good choices because they want to, not because they fear punishment.
  • They are pleasant to be around, and are more likely to have an easier time making friends.

Of course, how we discipline is as important as whether or not we discipline. Disciplining a child does not mean yelling or losing one’s temper (though being human, all parents can certainly have those moments when we can get angry or frustrated by a child’s bad behavior).

The key to positive child discipline is keeping your cool (and giving yourself a time out if necessary) so that you can communicate with your child calmly about what is and is not acceptable behavior and how he can make better choices and learn from his mistakes.

I come from a species called humans and through evolution (if you believe in that) we supposedly descended from ape like creatures.  It is embarrassing for me to say I come from the same species as those individuals you were shown on TV in Missouri beating up on each other this past year.  Memphis police say as many as 125 teenagers were involved in that Saturday melee — that left two other people injured. Authorities believe the young thugs were playing a game called “point them out, knock them out.”  This knock out game that has been shown on our T.V.’s in our living rooms happened throughout America which started earlier this past year.   Than what are people in society all over America hanging the cops for doing everything they do by RIOTING (not protesting which are media calls it, what a joke) is really effective.  There is good, bad and ugly in every race, gender, job and will always be that way  One reason for our young ones acting this way is because of no discipline in being brought up.  You need rules, regulations outlined by your parents for structure and organization for the child to know how to behave appropriately to other individuals and know what is right and wrong.  Otherwise you have chaos like this and so many other examples.  Examples like people walking over each other in Walmart Xmas time, , beating up on complete strangers for fun (at least baboons due it to protect their own species).  We on the other hand beat up on each other for fun, or have a fight with our wife than drag her out of an elevator, too many young men robbing old ladies for their money or jewelry after knocking them over with their walker.  Than we have the bullying in schools that continues on in college causing very young adults to resort to suicide from bullying still going on in college.  Pretty low life if you ask me.  I could go on with examples but more important lets look at what discipline actually does for the child in childhood and later as an adult.  Ending line with disciplining your children the higher the odds the child will deal with life more effective being productive in society. Especially if they can learn what winning and losing is and not being hidden in their childhood by allowing schools to teach them everybody wins because that is not true in life.

 

QUOTE FOR MONDAY:

“Sugar in any form causes obesity and disease when consumed in pharmacologic doses.Cane sugar and high fructose corn syrup are indeed both harmful when consumed in pharmacologic doses of 140 pounds per person per year.”

Dr. Mark Hyman http://drhyman.com/blog/2011/05/13/5-reasons-high-fructose-corn-syrup-will-kill-you/#close

The danger of Fructose Corn Syrup for Many Reasons.

You might think that the increase of the use of “high-fructose corn syrup during the past 30 years, would be safe. High Fructose Corn Syrup (HFCS) is an “artificial” sweetener made from a complex process with corn; a process of brewing, separating, breaking down, injecting enzymes, filtering, mixing and blending.  Sounds safe enough, doesn’t it?

High fructose corn syrup is extremely soluble and mixes well in many foods. It is cheap to produce, sweet and easy to store. It’s used in everything from bread to pasta sauces to bacon to beer as well as in “health products” like protein bars and “natural” sodas.

HFCS is less expensive, lasts longer, and is more easily transported and handled than natural sugar; thus food producers prefer it for their manufacturing processes.

Research has shown that “high-fructose corn syrup” goes directly to the liver, releasing enzymes that instruct the body to then store fat! This may elevate triglyceride (fat in blood) levels and elevate cholesterol levels. Because it is metabolized by the liver, fructose does not cause the pancreas to release insulin the way it normally does. Fructose converts to fat more than any other sugar. Fructose reduces the affinity of insulin for its receptor, which is the hallmark of type-2 diabetes.

Some research claims that HFCS does not metabolize in the body like regular “natural” sugars; and that it might cause obesity-related glitches within the liver and other organs which normally deal with metabolizing, storing and using sugars in the body.

HFCS is Often Contaminated with Mercury. Recent studies of samples of HFCS and food products containing it in the United States conducted via two studies found that between 31% and 45% of the samples contained mercury. Mercury is toxic in even small quantities. For years, there have been suspicions that mercury used in vaccines may be related to the rise in autism in the United States. But this mercury contamination issue is much bigger and affects common foods widespread throughout the nation’s food supply. Products tested from big-name manufacturers such as Minute Maid, Coca-Cola, Hershey’s, Quaker, Hunt’s, Manwich, Smucker’s, Kraft, Nutri-Grain, and Yoplait had detectable levels of mercury.

Today, Commercial fruit juices and any products containing high fructose corn syrup are more dangerous than sugar and should be removed from the diet.

Read Labels! You’ll quickly see that this ingredient has been added to half the supermarket. So read under Ingredients carefully and look for High Fructose Corn Syrup or even just Corn Syrup.