“Alagille syndrome can often be difficult to diagnose because it has signs and symptoms similar to those of other liver diseases, such as biliary atresia. There are several ways to diagnose Alagille syndrome, such as liver function tests, heart evaluations, eye exams, ultrasounds, and genetic testing.  Alagille syndrome can develop by chance with no history of the disease in the family. However, in up to 50% of cases, the disease is passed down from a parent.”

AlagilleSyndrome.com  (https://alagillesyndrome.com/?gclid=EAIaIQobChMIh5vN_q3j_AIVF_rICh0a1A5VEAAYASAAEgID4fD_BwE&gclsrc=aw.ds)

“It’s estimated that 6 out of 10 Americans suffer from a chronic disease, and 4 of those 10 suffer from two or more. These diseases include: type 2 diabetes, Alzheimer’s, stroke, heart disease, cancer, chronic kidney disease and chronic lung disease.”

Centers for Disease Control and Prevention (CDC)

4 IN 10                                                              6 in 10

Adults in the U.S.                                         Adults in the U.S.

Have two or more                                         have a chronic disease     

The CDC; states Chronic diseases—such as heart disease, cancer, and diabetes—are the leading causes of death and disability in the United States. They are also leading drivers of the nation’s $4.1 trillion in annual health care costs.

Most chronic diseases are caused by key risk behaviors:

• Tobacco use and exposure to secondhand smoke.
• Poor nutrition, including diets low in fruits and vegetables and high in sodium and saturated fats.
• Physical inactivity.
• Excessive alcohol use.

These behaviors can lead to conditions such as high blood pressure or obesity, which raise the risk of the most common and serious chronic diseases.

The top 10 leading causes of death are still heart disease, cancer, diabetes, stroke and cerebral vascular diseases, chronic lower respiratory diseases, kidney disease, alzheimer’s disease, suicide, unintentional injuries and influenza and pneumonia.

1. Heart Disease

Number of deaths per year: 635,260

Percent of total deaths: 23.1 percent

More common among:

• men
• people who smoke
• people who are overweight or obese
• people with a family history of heart disease or heart attack
• people over age 55

Remember the heart is our engine to our body; without the engine we die!  Heart disease runs into many other problems that would not develope without heart disease!

Tips in helping a person live longer and probably more productive with even possibly happier life:

Lifestyle changes can prevent many cases of heart disease and other diseases, such as the following:

• Quit smoking.
• Eat a healthier diet.
• Exercise at least 30 minutes per day, five days a week.
• Maintain a healthy weight.

“Anger can be a common emotion among people experiencing major depression. You may feel angry at the world, angry about events from your past, or even angry at yourself. This anger can be intense and difficult to control, to the point that it worsens your depression and affects your personal and professional relationships”.

Very Well Mind (https://www.verywellmind.com/connection-between-depression-and-anger)

Depression versus Anger —What does it all mean & What do I do?

Getting the blues  or down in the dumps now and than in one thing but staying in the blues or down in the dumps just sinking deeper over a long period of time can be diagnosed as clinical depression. Clinical depression presents many forms and symptoms. It is not something just to be brushed off, assuming it will rectify itself in a while. One of the most common symptoms noted when a person suffers from clinical depression is anger. Whether it’s uncontrollable anger toward oneself or outward aggression toward others, it’s clinically proven that depression and anger run hand in hand.

Do you find yourself feeling angry more often than usual, or more often than not, depression could be to blame. Anger is a common symptom of depression, which can lurk beneath the surface of any man, woman, or child as well.

Depressive disorders come in many different types, but each type has its own unique symptoms and treatments. Major depression, the most common type of a depressive disorder, is characterized by a combination of symptoms (see symptom list) that interfere with the ability to work, study, sleep, eat, and enjoy once pleasurable activities. Such a disabling episode of depression may occur only once but more commonly occurs several times in a lifetime. Mental health professionals use this checklist of specific symptoms to determine whether major depression exists or not. Depression is also rated by your diagnosing physician or mental health professional in terms of its severity — mild, moderate, or severe. Severe depression is the most serious type. A less severe type of depression, dysthymia, involves long-term, chronic symptoms that do not disable, but keep one from functioning well or from feeling good. Many people with dysthymia also experience major depressive episodes at some time in their lives. Another type of depression is experienced as a part of bipolar disorder, also called manic-depressive illness. Not nearly as prevalent as other forms of depressive disorders, bipolar disorder is characterized by cycling mood changes: severe highs (mania) and lows (depression). Sometimes the mood switches are dramatic and rapid, but most often they are gradual. When in the depressed cycle, an individual can have any or all of the symptoms of a depressive disorder. When in the manic cycle, the individual may be overactive, overtalkative, and have a great deal of energy. Mania often affects thinking, judgment, and social behavior in ways that cause serious problems and embarrassment. For example, the individual in a manic phase may feel elated, full of grand schemes that might range from unwise business decisions to romantic sprees.

Risk Factors:

Numerous risk factors can lead to feelings of depression and anger in an individual. Some of these risk factors include but are not limited to: loneliness, financial strain, unemployment, alcohol or drug abuse, marital or family problems, or lack of a social support network. Depression and anger can also be influenced by childhood trauma, or it can be hereditary.

Symptoms

         Anger

Anger manifested with depression is no ordinary anger. It can be all-consuming feelings of anger and hatred against one’s self, others or the situation that is causing the depression. One of the first signs of depression in a teenager may be a sudden onset of uncontrollable anger. In turn, constant feelings of anger can also trigger a response of depression. Also anger noted with depression are a tendency to turn away from family and friends, poor performance at work or school, lack of motivation, feelings of guilt, insomnia and hopelessness

Not everyone who is depressed or manic experiences every symptom. Some people experience a few symptoms, some many. Severity of symptoms varies with individuals and also varies over time.

           Depression

• Persistent sad, anxious, or “empty” mood
• Feelings of hopelessness, pessimism
• Feelings of guilt, worthlessness, helplessness
• Loss of interest or pleasure in hobbies and activities that were once enjoyed, including sex
• Decreased energy, fatigue, being “slowed down”
• Difficulty concentrating, remembering, or making decisions
• Insomnia, early-morning awakening, or oversleeping
• Appetite and/or weight loss or overeating and weight gain
• Thoughts of death or suicide; suicide attempts
• Restlessness, irritability
• Persistent physical symptoms that do not respond to treatment, such as headaches, digestive disorders, and chronic pain.Symptoms of Mania (for Bipolar Disorder)
• Unusual irritability
• Decreased need for sleepGrandiose notions
• Increased talking
• Racing thoughts
• Increased sexual desire
• Markedly increased energy
• Poor judgment
• Inappropriate social behavior

What to do about it:

Depression often won’t improve without support from a trained mental health professional unless you know how to look at life in a positive way and know the results won’t always be in your favor.  Try to put what is best for others and not always best for you. Therapy can have a lot of benefit for anger, too — though it’s certainly possible to learn to control anger on your own.

1. Count down

Count down (or up) to 10. If you’re really mad, start at 100. In the time it takes you to count, your heart rate will slow, and your anger will likely subside.

2. Take a breather

Your breathing becomes shallower and speeds up as you grow angry. Reverse that trend (and your anger) by taking slow, deep breaths from your nose and exhaling out of your mouth for several moments.

3. Go walk around

Exercise can help calm your nerves and reduce anger. Go for a walk, ride your bike, or hit a few golf balls. Anything that gets your limbs pumping is good for your mind and body.

4. Relax your muscles

Progressive muscle relaxation calls on you to tense and slowly relax various muscle groups in your body, one at a time. As you tense and release, take slow, deliberate breaths.

5. Repeat a mantra

Find a word or phrase that helps you calm down and refocus. Repeat that word again and again to yourself when you’re upset. “Relax,” “Take it easy, and “You’ll be OK” are all good examples.

6. Stretch

Neck rolls and shoulder rolls are good examples of nonstrenuous yoga-like movements that can help you control your body and harness your emotions. No fancy equipment required.

7. Mentally escape

Slip into a quiet room, close your eyes, and practice visualizing yourself in a relaxing scene. Focus on details in the imaginary scene: What color is the water? How tall are the mountains? What do the chirping birds sound like? This practice can help you find calm amidst anger.

8. Play some tunes

Let music carry you away from your feelings. Put in earbuds or slip out to your car. Crank up your favorite music and hum, bop, or sashay your anger away.

9. Stop talking

When you’re steamed, you may be tempted to let the angry words fly, but you’re more likely to do harm than good. You may something you regret that some would never forgive you; remember its easy to say I forgive you but most don’t forget it including they may forget all the good you did in some cases.  Pretend your lips are glued shut, just like you did as a kid. This moment without speaking will give you time to collect your thoughts.

10. Take a timeout

Give yourself a break. Sit away from others. In this quiet time, you can process events and return your emotions to neutral. You may even find this time away from others is so helpful you want to schedule it into your daily routine.

11. Take action

Harness your angry energy. Sign a petition. Write a note to an official. Do something good for someone else. Pour your energy and emotions into something that’s healthy and productive.

12. Write in your journal

What you can’t say, perhaps you can write. Jot down what you’re feeling and how you want to respond. Processing it through the written word can help you calm down and reassess the events leading up to your feelings.

13. Find the most immediate solution

You might be angry that your child has once again left their room a mess before going to visit a friend. Shut the door. You can temporarily end your anger by putting it out of your view. Look for similar resolutions in any situations.

14. Rehearse your response

Prevent an outburst by rehearsing what you’re going to say or how you’re going to approach the problem in the future. This rehearsal period gives you time to role-play several possible solutions, too.

15. Picture a stop sign

The universal symbol to stop can help you calm down when you’re angry. It’s a quick way to help you visualize the need to halt yourself, your actions, and walk away from the moment.

16. Change your routine

If your slow commute to work makes you angry before you’ve even had coffee, find a new route. Consider options that may take longer but leave you less upset in the end.

17. Talk to a friend

Don’t stew in the events that made you angry. Help yourself process what happened by talking with a trusted, supportive friend who can possibly provide a new perspective.

18. Laugh

Nothing upends a bad mood like a good one. Diffuse your anger by looking for ways to laugh, whether that’s playing with your kids, watching stand-up, or scrolling memes.

19. Practice gratitude

Take a moment to focus on what’s right when everything feels wrong. Realizing how many good things you have in your life can help you neutralize anger and turn around the situation.

20. Set a timer

The first thing that comes to mind when you’re angry likely isn’t the thing you should say. Give yourself a set time before you respond. This time will help you be calmer and more concise.

21. Write a letter

Write a letter or email to the person that made you angry. Then, delete it. Often, expressing your emotions in some form is all you want, even if it’s in something that will never be seen.

22. Imagine forgiving them

Finding the courage to forgive someone who has wronged you takes a lot of emotional skill. If you can’t go that far, you can at least pretend that you’re forgiving them, and you’ll feel your anger slip away.

23. Practice empathy

Try to walk in the other person’s shoes and see the situation from their perspective. When you tell the story or relive the events as they saw it, you may gain a new understanding and become less angry.

24. Express your anger

It’s OK to say how you feel, as long as you handle it in the right way. Ask a trusted friend to help you be accountable to a calm response. Outbursts solve no problems, but mature dialogue can help reduce your stress and ease your anger. It may also prevent future problems.

25. Find a creative channel

Turn your anger into a tangible production. Consider painting, gardening, or writing poetry when you’re upset. Emotions are powerful muses for creative individuals. Use yours to reduce anger.

The bottom line

Anger is a normal emotion that everyone experiences from time to time. However, if you find your anger turns to aggression or outbursts, you need to find healthy ways to deal with anger.  It is much better to take a step in controlling it rather than sitting around doing nothing.  For if your like that all the time would you like to be around people like that on your day off to relax.  I would think no.  If you don’t control it you may loose a lot you have in your life now and regret it later going to depression!  It is not worth it.

If these tips don’t help, consider talking with your doctor. A mental health specialist or therapist can help you work through underlying factors that may contribute to anger and other emotional issues.

“The New York Times reported that mental health providers have experienced an increased demand for services and a resulting “disenfranchised grief,” defined as a sense of loss related to safety, goals, social connections, and activities, accompanied by a sense of not having a right to grieve these losses because others have it worse [26]. USA Today noted that mental health providers have reported a flood of new clients, an overwhelming need to train others, and increased demand to both help stressed coworkers and deal with tougher cases (i.e, more intimate partner violence, systemic racism, clients placing themselves at risk). Their workloads have resulted in teletherapy fatigue, and they have reported guilt regarding answers they could not give, people they had to turn away, potentially exposing loved ones to COVID-19, or for taking time off to recover from COVID-19. They also noted that they had lost their normal coping strategies, such as decompressing on the drive home, stopping to speak with colleagues between clients, and socializing with friends.”

National Library of Medicine (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860255/)

One way of looking at life is whatever challenges comes your way know you will survive and for any losses you may experience when looking back on them take the positive aspects or memories not the negative that builds a bad effect on you (Ex. Insomnia to depression to high blood pressure to alcoholism to drugs).   A positive effect can be as simple as a smile when reflecting memories, which FYI allows less frowning that will cause less wrinkles on the forehead, as we get older.  Sometimes it’s not that simply and when it gets harder take up a constructive way of dealing with it (Ex. Work out at your level, walking, singing, go to a comedy movie, get together with friends go out, and do anything that gets your mind off of the stress and even out of your body through work out at the gym to just biking or walking.).

For starters stress is a body reaction to CHANGE.  How to you look at change?  Easy, positive!  It may not appear easy at first but try to look at this change as a sense of difficulty yet a challenge with a victory in the end, if approached right.  Let us take the following challenges, for example –  Having a child leave home for college or marriage, losing a home with this economy, a loss of a friend or family member in your life:  How do you look at these experiences positive?

Well for the child I would be so happy for her or him starting college life with my worries but know I raised her or him well and if he makes mistakes on the way he will learn to get up off the ground and fix them knowing he can come to me or dad whenever he has the need or if we sense a problem we would address it (Its part of life=growing up).  Another aspect to look at regarding this stress is there is loss in the parent role so fill up that loss with a new hobby, or get active in whatever organization you are in (Ex. Church, Temple, School, to just taking up ceramics or do more traveling with your spouse and friends).   I had my falls with the stresses that I have come across but got up every time to stand again, some quicker than other times.  If I can do it so can you.

How do you deal with losing a home or a job with this economy now; well appreciate the good memories you had when you had the home and pick up starting a new life elsewhere with making it a journey down the yellow brick road leading you to where the rainbow is at the end; don’t look at it as a loss.  As for the job you once found a job position and will find another in few weeks to few months depending on the Corona Virus and great economy we have since our last election.

Dealing with losing a family member or friend, again, the way I look at it is I appreciate the time I had with her or him and know they haven’t left me in spirit (if deceased).   If the person is still living know there are reasons for everything; whatever the cause was for the reason for the relationship parting and when out of my control I think of how I had a good friendship as opposed to never having one with that individual.  I accept that nothing lasts forever or indefinitely, with appreciating the time I may have had with the person.  Ending note is I look at life this way, whatever positive entity comes in my life may be taken away from me and appreciate every moment you spend with that person or thing in your life that you love so much (including my life span that only upstairs knows how long that time factor will be but I try to live a life at its healthiest optimal level with practicing positive behavior which is knowing whatever stressors come my way there is always someone worse off and with God I can face anything.

If I don’t deal with stress like this than I can expect complications that may arise, just like for anyone else who looks at challenges coming their way in a negative sense.  You commonly see stress become a negative experience when a person faces continuous challenges/stressors without relief or relaxation between the them.  The ending result is the person becomes overworked and stress-related tension builds.  Stress that continues without positive resolution at some level can cause a condition called distress, which is a negative stress reaction.

The physical reactions that happen to your body due to negative stress:

-Elevated high blood pressure –Headaches –Chest Pain –Upset Stomach   –Insomnia –Grinding of the teeth –Jaw Tension –Teeth grinded down –Irritability –Anger –Panic episodes –Vasoconstriction to our vessels   causing increases to the heart rate –Decreases sex drive –Depression (Research even suggests that stress also can bring on or worsen certain symptoms or diseases.)

Stress costs American industry more than $300 billion a year. WOW !                    

The lifetime prevalence of an emotional disorder is more than 50%, often due to chronic, untreated stress reactions.

Remember, Stress is a normal part of life.  Many events that happen to you and around you — and many things that you do yourself (Ex. Work 40 to 60 hrs a week in a highly stressful job, like a staff nurse) – this will put stress on your body. You can experience stress from your environment, your body, and your thoughts.  You can also cause the stress to impact your body with first just signs and symptoms (s/s) developing, that are listed above, but without relief of the stress these s/s can lead you into a disease/illness forming or even make the diagnose (s) you already have even worse.

Many signs and symptoms pick up when exposed to continual stress or stresses that just build up on top of each other causing some people in developing unhealthy habits, poor dieting, and the lack of desire to be as active as they were which in turn develops conditions that would not have occurred if this negative behavior didn’t happen over a long period of time.

This behavior with the stress or stresses you are experiencing increases the probability of health conditions starting to take place in your body or if you’re with certain diagnoses already the stress can possibly impact your body by worsening the condition.    The conditions that can develop from any age of being under continual stress over a period of time are:

-ADD or ADHD –Panic disorders –High blood pressure –Anti-arrhythmias -Cardiac Disease -Diabetes 1 or Diabetes 2  -Stroke –Irritable Bowel Syndrome –Weight Gain/Obesity –Fibromyalgia –Complex Regional Pain Syndrome –ETOH -Depression and so much more.

 How to bypass developing conditions that can be caused from the long constant stress or stresses you experience? One method is fight back (fight or flight), and when it gets really difficult don’t turn to bad heath patterns in your life to deal with the stressors turn to a healthy diet, keeping a healthy weight for your body mass index (BMI) so you can deal better with fighting the stressors in your life (if not sure what your BMI is check online to find out how to calculated it, it is for free), and practice healthy habits.  You may be saying how to I even go about that or maybe it’s easy for me but not true.  Let me shine some light on this topic.  I was there many times before and found a resolution to help deal better with my stresses through a change in eating and I lost 22 lbs. and still I am trying with being physically challenged at this moment to get to my optimal shape.  If you want to check out how to deal effectively with your stress and live a healthier life for prevention of complications.

Do what it best for you and the people in your community or country.  Go outside when you need to shop for foods or things needed at the house for you and the family.  If you have Covid without question stay home. If someone at home has covid positive quarantine that member in a room and have people in the house negative use the home covid tests to check that their still negative as well as feeling well before going out.  When going out wear a mask.

“In 2011, the Kawasaki Disease Foundation declared January 26 the first National Kawasaki Disease Awareness Day in the United States, and they presented the resolution before the 111th Congress, 2nd Session.  The Kawasaki Disease Foundation chose this date because, on January 26, 1961, Dr. Tomisaku Kawasaki of Japan had his “aha” moment when he saw his second patient with the telltale signs of what would later be named Kawasaki disease (KD). KD is the leading cause of acquired heart disease in U.S. children, but with effective treatment, only a small percentage of KD patients have lasting coronary artery damage.”.

Kawasaki Foundation (https://kdfoundation.org/kd101/)

Kawasaki disease (KD), also known as Kawasaki syndrome, is a severe illness characterized by inflammation of blood vessels throughout the body that primarily affects young children and infants. Kawasaki disease is the leading cause of acquired heart disease in children. Although about 80 percent of patients are under five years of age, older children and teenagers can also get KD, but this is uncommon. KD is more common in boys than girls, and the majority of cases are diagnosed in the winter and early spring. KD is not contagious.

The disease is named after Tomisaku Kawasaki, a Japanese pediatrician who first described the illness in the medical literature in 1967. Although it is more prevalent among children of Asian and Pacific Island descent, KD affects people of all racial and ethnic groups.

It is estimated that more than 4,200 children are diagnosed with Kawasaki Disease in the U.S. each year. The cause of KD is unknown, although an agent, like a virus, is suspected. There is no currently accepted scientific evidence that KD is caused by carpet cleaning or chemical exposure.

There is no specific test for KD; doctors make a clinical diagnosis based on a collection of symptoms and physical findings.

Symptoms

Kawasaki disease symptoms usually appear in three phases. Early symptoms of KD include:

Phase 1

• A fever that is often higher than 102.2 F (39 C) and lasts at least five days
• Bloodshot eyes (conjunctivitis) without a thick discharge
• A rash on the main part of the body (trunk) and/or in the genital area
• Red, dry, cracked lips and an extremely red, swollen tongue (strawberry tongue)
• Swollen, red skin on the palms of the hands and the soles of the feet
• Swollen lymph nodes in the neck

Phase 2

In the second phase of the disease, the symptoms may include:

• Peeling of the skin on the hands and feet, especially the tips of the fingers and toes
• Joint pain
• Diarrhea
• Vomiting
• Abdominal pain

Phase 3

In the third phase of the disease, signs and symptoms will slowly fade away unless complications develop. Patients experiencing Kawasaki disease may experience tiredness, irritability and low energy for as long as eight weeks post the initial diagnosis.

Treatment and Complications

To reduce the risk of coronary artery complications, treatment for KD shall be started within ten days of the onset of symptoms. Most KD patients will recover from KD without any lasting heart damage; however, without treatment, about 25% of KD patients will develop abnormalities of the coronary arteries. Treatment for KD may include:

• Gamma globulin (to lower the risk of coronary artery problems)
• Aspirin (to treat inflammation, decrease pain and joint inflammation, as well as reduce the fever)

Kawasaki treatment is a rare exception to the rule against aspirin use in children but only when given under the supervision of your child’s doctor. Children who develop coronary artery abnormalities may be required to continue taking aspirin for six weeks or longer to prevent clotting. Taking aspirin has been linked to Reye’s Syndrome, a rare but potentially life-threatening condition that can affect the blood, liver, and brain of children and teenagers after a viral infection. Children who develop chickenpox or the flu during aspirin treatment may be required to stop taking aspirin.

” An estimated 300,000 children in the U.S. — that’s 1 in 250 kids — are affected by some form of JA. This disease takes a unique physical and emotional toll on kids, often resulting in debilitating pain and feelings of loneliness or depression. JA can make it especially challenging for kids to say Yes — Yes to playing, Yes to hanging out with friends, Yes to spending time with family, Yes to being a kid!”

Arthritis Foundation  (http://blog.arthritis.org/juvenile-arthritis/)