“The single best way to reduce the risk of seasonal flu and its potentially serious complications is to get vaccinated each year, but good health habits like avoiding people who are sick, covering your cough and washing your hands often can help stop the spread of germs and prevent respiratory illnesses like flu.”
Centers for Disease Control and Prevention – CDC (https://www.cdc.gov)
“Symptoms of a cold tend to be mild. You may have a runny nose, cough, congestion, and sore throat. But you won’t usually have the aches and fever that are common with COVID-19 and flu. Often, you’ll feel better in a couple of days.
There’s no cure for the common cold. Typical treatments include rest, fluids, and over-the-counter medicines. Winter is the prime cold and flu season. You’re more likely to be indoors and closer to others when it’s colder outside. Weather also plays a role in the spread of viruses.”
NIH News in Health
“People with an increased risk of lung cancer may consider annual lung cancer screening using low-dose CT scans. Lung cancer screening is generally offered to older adults who have smoked heavily for many years or who have quit in the past 15 years. If there’s reason to think that you may have lung cancer, your doctor can order a number of tests to look for cancerous cells and to rule out other conditions. An X-ray image of your lungs, a sample of abnormal cells may be removed in a procedure called a biopsy, and doing the staging of the cancer.”
MAYO CLINIC
“The two major types of lung cancer are small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC).
SCLC accounts for about 13 percentTrusted Source of all lung cancers. It’s less common than NSCLC, according to the American Cancer Society (ACS).
However, SCLC is the more aggressive form of lung cancer. With SCLC, the cancer cells tend to grow quickly and travel to other parts of the body, or metastasize, more easily.
Though the majority of lung cancer cases are non-small cell lung cancer (NSCLC). Doctors stage NSCLC according to how far it has progressed. Stages range from occult (or hidden) cancer to stage 4 cancer, in which multiple organs may be affected.
The staging system helps doctors determine the best treatment plan, and helps individuals with cancer and their families understand the severity of the disease and the outlook.
There are several different staging systems used around the world, but the most widely used approach is known as the TNM system.”
healthline (https://www.healthline.com/health/lung-cancer-small-cell)
Small and non-small cell lung cancers cause similar symptoms. Sometimes, symptoms do not appear until the cancer reaches a later stage. The symptoms of small and non-small cell lung cancers are similar, but small cell lung cancer spreads more rapidly. A person may be more likely to experience symptoms after lung cancer has reached a later stage. Shoulder pain often occurs due to inflammation or muscle injuries. Less frequently, shoulder pain can be a symptom of lung cancer. Although shoulder pain is not a common symptom of lung cancer, any persistent, unexplained pain warrants a visit to a doctor for further investigation. ”
Medical News Today (https://www.medicalnewstoday.com)
“One in five people worldwide develop cancer during their lifetime. Prevention of cancer has become one of the most significant public health challenges of the 21st century. It has a critical role to play in the fight against cancer. Based on current scientific evidence, at least 40% of all cancer cases could be prevented with effective primary prevention measures, and further mortality can be reduced through early detection of tumours.”
International Agency for Research on Cancer (https://www.iarc.who.int/cancer-topics)
“Williams syndrome (WS) is a genetic condition that is present at birth and can affect anyone. It is characterized by medical problems, including cardiovascular disease, developmental delays, and learning challenges. These often occur side by side with striking verbal abilities, highly social personalities, and an affinity for music. WS occurs equally in males and females and in all cultures worldwide. Williams syndrome is caused by the spontaneous deletion of 26-28 genes on chromosome #7 at the time of conception. The deletion can occur in either the egg or the sperm. It is likely that in most families, the child with Williams syndrome is the only one to have the elastin gene condition in his or her entire extended family. There are two DNA tests that can determine if a person has Williams syndrome. The FISH test and the Microarray.”
William Syndrome (https://williams-syndrome.org/what-is-ws)
Williams syndrome (WS) is a genetic condition that is present at birth and can affect anyone. It is characterized by medical problems, including cardiovascular disease, developmental delays, and learning disabilities. The most significant medical problem associated with WS is the cardiovascular disease caused by the narrowed arteries. WS is also associated with elevated blood calcium levels in infancy. A random genetic mutation (deletion of a small piece of chromosome 7), rather than inheritance, most often causes the disorder. Williams syndrome is considered an autosomal dominant condition because one copy of the altered chromosome 7 in each cell is sufficient to cause the disorder. In a small percentage of cases, people with Williams syndrome inherit the chromosomal deletion from a parent with the condition.
Most cases of Williams syndrome are not inherited but occur as random events during the formation of reproductive cells (eggs or sperm) in a parent of an affected individual. These cases occur in people with no history of the disorder in their family.
However, individuals who have WS have a 50 percent chance of passing it on if they decide to have children. These often occur side by side with striking verbal abilities, highly social personalities and an affinity for music.
WS affects 1 in 7,500 – 10,000 people worldwide – an estimated 20,000 to 30,000 people in the United States. It is known to occur equally in both males and females and in every culture.
Unlike disorders that can make connecting with your child difficult, children with Williams syndrome tend to be social, friendly and endearing. Parents often say the joy and perspective a child with WS brings into their lives had been unimaginable.
But there are major struggles as well. Many babies have life-threatening cardiovascular problems. Children with WS need costly and ongoing medical care and early interventions (such as speech or occupational therapy) that may not be covered by insurance or state funding. As they grow, they struggle with things like spatial relations, numbers, and abstract reasoning, which can make daily tasks a challenge. As adults, most people with Williams syndrome will need supportive housing to live to their fullest potential. Many adults with WS contribute to their communities as volunteers or paid employees; often working at assisted living homes for senior citizens, hospitals and libraries, or as store greeters or veterinary aides.
However, individuals who have WS have a 50 percent chance of passing it on if they decide to have children. The characteristic facial features of WS include puffiness around the eyes, a short nose with a broad nasal tip, wide mouth, full cheeks, full lips, and a small chin. People with WS are also likely to have a long neck, sloping shoulders, short stature, limited mobility in their joints, and curvature of the spine. Some individuals with WS have a star-like pattern in the iris of their eyes. Infants with WS are often irritable and colicky, with feeding problems that keep them from gaining weight. Chronic abdominal pain is common in adolescents and adults. By age 30, the majority of individuals with WS have diabetes or pre-diabetes and mild to moderate sensorineural hearing loss (a form of deafness due to disturbed function of the auditory nerve). For some people, hearing loss may begin as early as late childhood. WS also is associated with a characteristic “cognitive profile” of mental strengths and weaknesses composed of strengths in verbal short-term memory and language, combined with severe weakness in visuospatial construction (the skills used to copy patterns, draw, or write). Most older children and adults with WS speak fluently and use good grammar. More than 50% of children with WS have attention deficit disorders (ADD or ADHD), and about 50% have specific phobias, such as a fear of loud noises. The majority of individuals with WS worry excessively.
Unfortunately there is no cure for Williams syndrome, nor is there a standard course of treatment.
The prognosis for individuals with WS varies. Some degree of impaired intellect is found in most people with the disorder. Some adults are able to function independently, complete academic or vocational school, and live in supervised homes or on their own; most live with a caregiver.
Where you can find additional information about Williams syndrome:
You may find the following resources about Williams syndrome helpful. These materials are written for the general public.
“Your kidneys and circulatory system depend on each other for good health. The kidneys help filter wastes and extra fluids from blood, using a lot of blood vessels. When the blood vessels become damaged, the nephrons that filter your blood don’t receive the oxygen and nutrients they need to function well. This is why high blood pressure is the second leading cause of kidney failure.”
heart.org (https://www.heart.org/en/health-topics/high-blood-pressure/health-threats-from-high-blood-pressure/how-high-blood-pressure-can-lead-to-kidney-damage-or-failure)
Blood pressure is the force of blood pushing against blood vessel walls as your heart pumps out blood. High blood pressure NIH external link, also called hypertension, is an increase in the amount of force that blood places on blood vessels as it moves through the body.
Healthy kidneys filter about a half cup of blood every minute, removing wastes and extra water to make urine. The urine flows from each kidney to the bladder through a pair of thin tubes called ureters, one on each side of your bladder. Your bladder stores urine. Your kidneys, ureters, and bladder are part of your urinary tract system.
High blood pressure can constrict and narrow the blood vessels, which eventually damages and weakens them throughout the body, including in the kidneys. The narrowing reduces blood flow.
If your kidneys’ blood vessels are damaged, they may no longer work properly. When this happens, the kidneys are not able to remove all wastes and extra fluid from your body. Extra fluid in the blood vessels can raise your blood pressure even more, creating a dangerous cycle, and cause more damage leading to kidney failure.
Almost 1 in 2 U.S. adults—or about 108 million people—have high blood pressure.1
More than 1 in 7 U.S. adults—or about 37 million people—may have chronic kidney disease (CKD).
High blood pressure is the second leading cause of kidney failure in the United States after diabetes, as illustrated in Figure 1.
You are more likely to have high blood pressure if you
In addition to high blood pressure, other factors that increase your risk of kidney disease are
High blood pressure can be both a cause and a result of kidney disease.
Most people with high blood pressure do not have symptoms. In rare cases, high blood pressure can cause headaches.
Early CKD also may not have symptoms. As kidney disease gets worse, some people may have swelling, called edema. Edema happens when the kidneys cannot get rid of extra fluid and salt. Edema can occur in the legs, feet, ankles, or—less often—in the hands or face.
Symptoms of advanced kidney disease can include
Blood pressure test results are written with the two numbers separated by a slash. The top number is called the systolic pressure and represents the pressure as the heart beats and pushes blood through the blood vessels. The bottom number is called the diastolic pressure and represents the pressure as blood vessels relax between heartbeats.
Your health care professional will diagnose you with high blood pressure if your blood pressure readings are consistently higher than 130/80 when tested repeatedly in a health care office.
Health care professionals measure blood pressure NIH external link with a blood pressure cuff. You can also buy a blood pressure cuff to monitor your blood pressure at home.
To check for kidney disease, health care professionals use
If you have kidney disease, your health care professional will use the same two tests to monitor your kidney disease.
The best way to slow or prevent kidney disease from high blood pressure is to take steps to lower your blood pressure. These steps include a combination of medicines and lifestyle changes, such as
No matter what the cause of your kidney disease, high blood pressure can make your kidneys worse. If you have kidney disease, you should talk with your health care professional about your individual blood pressure goals and how often you should have your blood pressure checked.
Medicines that lower blood pressure can also significantly slow the progression of kidney disease. Two types of blood pressure-lowering medications, angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs), may be effective in slowing the progression of kidney disease.
Many people require two or more medications to control their blood pressure. In addition to an ACE inhibitor or an ARB, a health care professional may prescribe a diuretic—a medication that helps the kidneys remove fluid from the blood—or other blood pressure medications NIH external link.
Regular physical activity can lower your blood pressure and reduce your chances of other health problems.
Aim for at least 150 minutes per week of moderate-intensity aerobic activity. These activities make your heart beat faster and may cause you to breathe harder. Start by trying to be active for at least 10 minutes at a time without breaks. You can count each 10-minute segment of activity toward your physical activity goal. Aerobic activities include
If you have concerns, a health care professional can provide information about how much and what kinds of activity are safe for you.
If you are overweight or have obesity, aim to reduce your weight by 7 to 10 percent during the first year of treatment for high blood pressure. This amount of weight loss can lower your chance of developing health problems related to high blood pressure.
Body Mass Index (BMI) is the tool most commonly used to estimate and screen for overweight and obesity in adults. BMI is a measure based on your weight in relation to your height. Your BMI can tell if you are at a normal or healthy weight, are overweight, or have obesity.
Your goal should be a BMI lower than 25 to help keep your blood pressure under control.3
If you smoke, you should quit. Smoking can damage blood vessels, raise the chance of developing high blood pressure, and worsen health problems related to high blood pressure.
If you have high blood pressure, talk with your health care professional about programs and products to help you quit smoking.
Learning how to manage stress, relax, and cope with problems can improve your emotional and physical health. Some activities that may help you reduce stress include
Following a healthy eating plan can help lower your blood pressure. Reducing the amount of sodium in your diet is an important part of any healthy eating plan. Your health care professional may recommend the Dietary Approaches to Stop Hypertension (DASH) eating plan NIH external link. DASH focuses on fruits, vegetables, whole grains, and other foods that are healthy for your heart and lower in sodium, which often comes from salt. The DASH eating plan
A registered dietitian can help tailor your diet to your kidney disease. If you have congestive heart failure or edema, a diet low in sodium intake can help reduce edema and lower blood pressure. Reducing saturated fat and cholesterol can help control high levels of lipids, or fats, in the blood.
People with advanced kidney disease should speak with their health care professional about their diet.
If you have kidney disease, avoid foods and beverages that are high in sodium NIH external link.
Additional steps you can take to meet your blood pressure goals may include eating heart-healthy and low-sodium meals, quitting smoking, being active, getting enough sleep, and taking your medicines as prescribed. You should also limit alcoholic drinks—no more than two per day for men and one per day for women—because consuming too many alcoholic beverages raises blood pressure.
In addition, a health care professional may recommend that you eat moderate or reduced amounts of protein.
Proteins break down into waste products that the kidneys filter from the blood. Eating more protein than your body needs may burden your kidneys and cause kidney function to decline faster. However, eating too little protein may lead to malnutrition, a condition that occurs when the body does not get enough nutrients.
If you have kidney disease and are on a restricted protein diet, a health care professional will use blood tests to monitor your nutrient levels.