QUOTE FOR MONDAY:

“Sudden cardiac arrest is the abrupt loss of heart function, breathing and consciousness. The condition usually results from a problem with your heart’s electrical system, which disrupts your heart’s pumping action and stops blood flow to your body.

Sudden cardiac arrest isn’t the same as a heart attack, when blood flow to a part of the heart is blocked. However, a heart attack can sometimes trigger an electrical disturbance that leads to sudden cardiac arrest.”

MAYO CLINIC

QUOTE FOR WEEKEND:

“Sarcoma is a rare cancer in adults and accounts for just 1% of all cancer diagnoses in the United States, where there will be estimated 13,130 new cases in 2020. Worldwide, the most common form of this cancer type is Kaposi’s sarcoma, which was diagnosed in an estimated 42,000 people and caused about 20,000 deaths in 2018. ”

Cancer Research Institute

QUOTE FOR FRIDAY:

“During Sarcoma Awareness Month we aim to further highlight the extraordinary challenges that sarcoma patients face and the need for more sarcoma research and better sarcoma therapies.”

Sarcoma Foundation of America SFA

QUOTE FOR WEDNESDAY:

“Moebius syndrome was originally described by German ophthalmologist Alfred Graefe in 1880, but is named for German neurologist Paul Julius Moebius, who reported features of this condition in 1888.

The incidence of Moebius syndrome is roughly 2 to 20 cases per million births. The condition occurs in all ethnicities. There is no gender bias (males and females are affected equally). At present, the etiology of Moebius syndrome is currently poorly understood, but may be due to genetic and/or environmental factors.

In very rare cases, a change in specific genes may be causative of Moebius syndrome.  Additionally, there are several other separate conditions with similarities to Moebius syndrome that have identified genetic etiologies.”

MOEBIUS syndrome foundation  (https://moebiussyndrome.org)

QUOTE FOR TUESDAY:

“Moebius syndrome is a rare neurological condition that primarily affects the muscles that control facial expression and eye movement. Signs and symptoms of the condition may include weakness or paralysis of the facial muscles; feeding, swallowing, and choking problems; excessive drooling; crossed eyes; lack of facial expression; eye sensitivity; high or cleft palate; hearing problems; dental abnormalities; bone abnormalities in the hands and feet; and/or speech difficulties.”

GERD Genetic and Rare Diseases Information Center  (https://rarediseases.info.nih.gov)

QUOTE FOR THE WEEKEND:

“Yersiniosis is an infection caused most often by eating raw or undercooked pork contaminated with Yersinia enterocolitica bacteria. CDC estimates Y. enterocolitica causes almost 117,000 illnesses, 640 hospitalizations, and 35 deaths in the United States every year. Children are infected more often than adults, and the infection is more common in the winter.”

CDC

QUOTE FOR FRIDAY:

“Hereditary hemochromatosis (he-moe-kroe-muh-TOE-sis) causes your body to absorb too much iron from the food you eat. Excess iron is stored in your organs, especially your liver, heart and pancreas. Too much iron can lead to life-threatening conditions, such as liver disease, heart problems and diabetes.

The genes that cause hemochromatosis are inherited, but only a minority of people who have the genes ever develop serious problems. Signs and symptoms of hereditary hemochromatosis usually appear in midlife.”

MAYO CLINIC

QUOTE FOR THURSDAY:

“Mismanaged iron in the brain has been observed in autopsies of people with neurodegenerative diseases: Alzheimer’s, early onset Parkinson’s, epilepsy, multiple sclerosis, and Huntington’s disease.

Caucasians are the people most at risk for the classic type of hemochromatosis. More than one million Americans have the genes for this type. However, there are other gene combinations that result in hemochromatosis regardless of a person’s ethnicity. It is estimated that as much as or more than 16 million Americans have some degree of elevated iron and are at risk for the same diseases that occur in people with the untreated classic type: bone and joint disease, cirrhosis, liver cancer, diabetes, hypothyroidism, hypogonadism, infertility, impotence, depression, or premature death due to liver or heart failure.”

hemochromatosis.org/

Part I Hemochromatosis

Hemochromatosis is a disorder where too much iron builds up in your body. Sometimes it’s called “iron overload.”   Hemo meaning blood and chromatosis means pigmentation specifically : deposit of pigment in a normally unpigmented area or excessive pigmentation in a normally pigmented site.

Normally, your intestines absorb just the right amount of iron from the foods you eat. But in hemochromatosis, your body absorbs too much, and it has no way to get rid of it. So, your body stores the excess iron in your joints and in organs like your liver, heart, and pancreas. This damages them. If it’s not treated, hemochromatosis can make your organs stop working.

There are two types of this condition — primary and secondary.

Primary hemochromatosis is hereditary, meaning it runs in families. If you get two of the genes that cause it, one from your mother and one from your father, you’ll have a higher risk of getting the disorder.

Secondary hemochromatosis happens because of other conditions you have. These include:

  • Certain kinds of anemia
  • Liver disease
  • Getting a lot of blood transfusions
  • White people of northern European descent are more likely to get hereditary hemochromatosis. Men are 5 times more likely to get it than women.

    Symptoms

    Up to half of people who have hemochromatosis don’t get any symptoms. In men, symptoms tend to show up between ages 30 and 50. Women often don’t show signs of this condition until they’re over 50 or past menopause. That may be because they lose iron when they get their periods and give birth.

    Symptoms of hemochromatosis include:

    • Pain in your joints, especially your knuckles
    • Feeling tired
    • Unexplained weight loss
    • Skin that has a bronze or gray color – pigmentation
    • Pain in your belly
    • Loss of sex drive
    • Loss of body hair
    • Heart flutter
    • Foggy memory

    Sometimes people don’t get any symptoms of hemochromatosis until other problems arise. These may include:

    • Liver
    • Diabetes
    • Abnormal heartbeat
    • Arthritis
    • Erectile dysfunction (difficulty having a erection)

    If you take a lot of vitamin C or eat a lot of foods that contain it, you can make hemochromatosis worse. That’s because vitamin C helps your body absorb iron from food.

    White people of northern European descent are more likely to get hereditary hemochromatosis. Men are 5 times more likely to get it than women.
     

QUOTE FOR WEDNESDAY:

“The arenaviruses are a family of viruses that are usually transmitted from rodents to humans and include viruses such as lymphocytic choriomeningitis (LCM), Lassa virus, Junin virus, and Machupo virus.”

Vaccines for Biodefense and Emerging and Neglected Diseases, 2009 through ScienceDirect (sciencedirect.com)