Through an accurate reference the Centers for Disease Control and Prevention, who wants to save lives and protect people, support the following:

Smoking is estimated to increase the risk—

• • For coronary heart disease by 2 to 4 times^1,6
  • For stroke by 2 to 4 times¹
  • Of men developing lung cancer by 25 times¹
  • Of women developing lung cancer by 25.7 times¹

Smoking causes diminished overall heath, such as self-reported poor health, increased absenteeism from work, and increased health care utilization and cost.

Smokers are at greater risk for diseases that affect the engine of the body=The heart and its branches=The circulatory system (putting a smoker at high risk for cardiovascular disease).

• Smoking causes stroke and coronary heart disease—the leading causes of death in the United States.
• Even people who smoke fewer than five cigarettes a day can have early signs of cardiovascular disease.
• Smoking damages blood vessels and can make them thicken and grow narrower. This makes your heart beat faster and your blood pressure go up. Clots can also form.
• A heart attack occurs when a clot blocks the blood flow to your heart. When this happens, your heart cannot get enough oxygen causing starvation of food, being oxygen to the heart tissue. This damages the heart muscle, and part of the heart muscle can die, which is what exactly happens with a heart attack where angina (lack of 02 is reversible).
• A stroke occurs when a clot blocks the blood flow to part of your brain or when a blood vessel in or around your brain bursts causing again starvation of food, being 02, just in a different tissue part. Get it oxygen is the food to all our tissues of the body
• Blockages caused by smoking can also reduce blood flow to your skin and legs (For example Peripheral Vascular Disease= PVD). Ever see the commercial with a person telling you to stop smoking with fingers surgically removed or limbs, PVD is what occurred to that individual and the person didn’t stop smoking. Due to this behavior what happened the vessels of the individual’s limbs became so narrowed that it cut off oxygenated blood supply to those tissue parts causing ischemia-lack of oxygen, which led to necrosis of the tissue (death) and the part had to be surgi-cally removed. Now that individual can’t walk or grasp things with those limbs that were operated on. Is smoking worth this consequence? I don’t think so, what about you? Just think about it if you still smoke.Smoking can cause lung disease by damaging your airways and the small air sacs (alveoli) found in your lungs. What actually happens to the lung tissue is the pin point openings (alveoli) keeps expanding to a wider opening. The alveoli is responsible of oxygen and carbon dioxide exchange when we inhale and exhale but with the alveoli stretched the exchange of the gases gets poor.
• Smoking effects the transmission of the body=The Lungs

• Lung diseases caused by smoking include COPD, which includes emphysema (especially) and chronic bronchitis.
• Cigarette smoking causes most cases of lung cancer.
• If you have asthma, tobacco smoke can trigger an attack or make an attack worse.^1,2
• Smokers are 12 to 13 times more likely to die from COPD than nonsmokers.

Smoking can cause cancer in almost every area of the body. If nobody smoked, one of every three cancer deaths in the United States would not happen. Smoking increases risk of dying from cancer and other diseases in cancer patients and survivors.

For those who quit smoking what risks you reduce:

• Quitting smoking cuts cardiovascular risks. Just 1 year after quitting smoking, your risk for a heart attack drops sharply.²
• Within 2 to 5 years after quitting smoking, your risk for stroke could fall to about the same as a nonsmoker’s.²
• If you quit smoking, your risks for cancers of the mouth, throat, esophagus, and bladder drop by half within 5 years.²
• Ten years after you quit smoking, your risk for lung cancer drops by half.

Again, if you smoke you may want to consider stopping; give it a thought.

“Bones support your body and allow you to move. They protect your brain, heart, and other organs from injury.

Bone is a living, growing tissue. It is made mostly of two materials: collagen (KOL-uh-juhn), a protein that provides a soft framework, and calcium (KAL-see-uhm), a mineral that adds strength and hardness. This combination makes bone strong and flexible enough to hold up under stress.

Bone releases calcium and other minerals into the body when you need them for other uses.

Think of your bones as a “bank” where you “deposit” and “withdraw” bone tissue. During your childhood and teenage years, new bone is added (or deposited) to the skeleton faster than old bone is removed (or withdrawn). As a result, your bones become larger, heavier, and denser.”

National Institute of Arthritis and Musculosketetal and Skin Disease (https://www.niams.nih.gov/health-topics/kids/healthy-bones)

“Gaucher disease can affect anyone, occurring in up to 1 in 40,000 live births in the general population.

Gaucher disease is more common among Jewish people of Ashkenazi (Eastern European) descent, occurring in approximately 1 in 450 within this population. As many as 1 in 10 may carry the mutated gene responsible for Gaucher disease.

Gaucher (go-SHAY) disease is the result of a buildup of certain fatty substances in certain organs, particularly your spleen and liver. This causes these organs to enlarge and can affect their function.  The fatty substances also can build up in bone tissue, weakening the bone and increasing the risk of fractures.  If the bone marrow is affected, it can interfere with your blood’s ability to clot.  An enzyme that breaks down these fatty substances doesn’t work properly in people with Gaucher disease.  Treatment often includes enzyme replacement therapy.”

National Gaucher Foundation (https://www.mayoclinic.org/diseases-conditions/gauchers-disease/symptoms-causes/syc-20355546)

Gaucher (go-SHAY) disease is the result of a buildup of certain fatty substances in certain organs, particularly your spleen and liver. This causes these organs to enlarge and can affect their function.

The fatty substances also can build up in bone tissue, weakening the bone and increasing the risk of fractures. If the bone marrow is affected, it can interfere with your blood’s ability to clot.

An enzyme that breaks down these fatty substances doesn’t work properly in people with Gaucher disease. Treatment often includes enzyme replacement therapy.

An inherited disorder, Gaucher disease is most common in Jewish people of Eastern and Central European descent (Ashkenazi). Symptoms can appear at any age.

Types of Gaucher Disease:

Scientists divide Gaucher disease into 3 different types based on the presence or absence of early-onset brain involvement, including:

• Gaucher disease type 1: Gaucher disease type 1 is the most common form of the disease in western countries, making up roughly 95 percent of patients there. Symptoms include spleen and liver enlargement, bone problems, and fatigue. Brain development is normal.
• Gaucher disease type 2: This type of Gaucher disease is rare and involves severe neurological (brain stem) abnormalities. It is usually fatal within the first 2 years, and it is currently untreatable because of the severe, irreversible brain damage.
• Gaucher disease type 3: This type of Gaucher disease is rare in the United States and Europe; however, it is the most common form of the disease worldwide. Gaucher disease type 3 has a severity between types 1 and 2, causing the same symptoms as type 1 plus some neurological involvement. While patients typically have a shortened lifespan, some can live into their 50s with treatment.

Symptoms

There are different types of Gaucher disease, and signs and symptoms of disease vary widely, even within the same type. Type 1 is by far the most common.

Siblings, even identical twins, with the disease can have different levels of severity. Some people who have Gaucher disease have only mild or no symptoms.

Most people who have Gaucher disease have varying degrees of the following problems:

• Abdominal complaints. Because the liver and especially the spleen can enlarge dramatically, the abdomen can become painfully distended.
• Skeletal abnormalities. Gaucher disease can weaken bone, increasing the risk of painful fractures. It can also interfere with the blood supply to your bones, which can cause portions of the bone to die.
• Blood disorders. A decrease in healthy red blood cells (anemia) can result in severe fatigue. Gaucher disease also affects the cells responsible for clotting, which can cause easy bruising and nosebleeds.

More rarely, Gaucher disease affects the brain, which can cause abnormal eye movements, muscle rigidity, swallowing difficulties and seizures. One rare subtype of Gaucher disease begins in infancy and typically results in death by 2 years of age.

Causes

Gaucher disease is passed along in an inheritance pattern called autosomal recessive. Both parents must be carriers of a Gaucher changed (mutated) gene for their child to inherit the condition.

Risk factors

People of Eastern and Central European Jewish (Ashkenazi) ancestry are at higher risk of developing the most common variety of Gaucher disease.

Complications

Gaucher disease can result in:

• Delays in growth and puberty in children
• Gynecological and obstetric problems
• Parkinson’s disease
• Cancers such as myeloma, leukemia and lymphoma

When to see a doctor

If you or your child has the signs and symptoms associated with Gaucher disease, make an appointment with your doctor ASAP.

“If you’ve been diagnosed with ovarian cancer, your cancer care team will discuss your treatment options with you. It’s important that you think carefully about each of your choices. Weigh the benefits of each treatment option against the possible risks and side effects.  Typically, treatment plans are based on the type of ovarian cancer, its stage, and any special situations. Most women with ovarian cancer will have some type of surgery to remove the tumor. Depending on the type of ovarian cancer and how advanced it is, you might need other types of treatment as well, either before or after surgery, or sometimes both. Typically the range of treatments are from surgery to chemo therapy, hormone therapy, targeted temperature therapy and/or immunotherapy depending on the oncologist team on the case.”

American Cancer Society (https://www.cancer.org/cancer/types/ovarian-cancer/treating.html)

“Ovarian cancer is the second most common gynecologic cancer in the United States. Ovarian cancer causes more deaths than any other cancer of the female reproductive system.  In 2020, the latest year for which incidence data are available, in the United States, 18,518 new cases of Ovarian cancer were reported among women, and 13,438 women died of this cancer. For every 100,000 women, 9 new Ovarian cancer cases were reported and 6 women died of this cancer.

Cancer is the second leading cause of death in the United States, exceeded only by heart disease. One of every five deaths in the United States is due to cancer.”

Centers for Disease Control and Prevention – CDC  (https://gis.cdc.gov/Cancer/USCS/#/AtAGlance/)

“In Lower Manhattan, the plane crashes—which resulted in the collapse of the Twin Towers—created massive dust clouds that filled the air and left hundreds of highly populated city blocks covered with ash, debris, and harmful particles, including asbestos, silica, metals, concrete, and glass. Fires within the debris pile and the collapse of 7 WTC burned through the end of December 2001 with continued flare-ups in 2002, releasing carcinogenic combustion by-products. These contaminants remained in Lower Manhattan and parts of Brooklyn for an undetermined amount of time after 9/11.”

Center for Disease Control and Prevention – CDC (https://www.cdc.gov/wtc/exhibition/toxins-and-health-impacts.html)

MEMORY OF 9/11

“Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive muscle degeneration and weakness due to the alterations of a protein called dystrophin that helps keep muscle cells intact. DMD is one of four conditions known as dystrophinopathies.  It is the most common type of muscular dystrophy.

DMD symptom onset is in early childhood, usually between ages 2 and 3. The disease primarily affects boys, but in rare cases it can affect girls.

In Europe and North America, the prevalence of DMD is approximately 6 per 100,000 individuals.DMD was first described by the French neurologist Guillaume Benjamin Amand Duchenne in the 1860s, but until the 1980s, little was known about the cause of any kind of muscular dystrophy. In 1986, MDA-supported researchers identified a particular gene on the X chromosome that, when flawed (mutated), leads to DMD. In 1987, the protein associated with this gene was identified and named dystrophin”

Muscular Dystrophy Association – MDA (https://www.mda.org/disease/duchenne-muscular-dystrophy)

The most common form of muscular dystrophy – Duchenne muscular dystrophy – typically affects young boys, but other variations can strike in adulthood.

Currently, there is no cure for muscular dystrophy, but certain physical and medical treatments can improve symptoms and slow the disease’s progression.

is a group of diseases that make muscles weaker and less flexible over time. It is caused by a problem in the genes that control how the body keeps muscles healthy. For some people, the disease starts early in childhood. Others don’t have any symptoms until they are teenagers or middle-aged adults.

How muscular dystrophy affects you or your child depends on the kind. Most people’s condition will get worse over time, and some people may lose the ability to walk, talk, or care for themselves. But that doesn’t happen to everyone. Other people can live for many years with mild symptoms.

There are more than 30 kinds of muscular dystrophy, and each is different based on:

• The genes that cause it
• The muscles it affects
• The age when symptoms first appear
• How quickly the disease gets worse

People usually get one of nine major forms of the disease:

• Duchenne muscular dystrophy (DMD) is the most common form. It mainly affects boys, and starts between ages 3 and 5.
• Becker muscular dystrophy is like Duchenne, except milder. It also affects boys but the symptoms start later — between ages 11 and 25.
• Myotonic muscular dystrophy is the most common form in adults. People who have it can’t relax their muscles after they contract. It can affect both men and women, and it usually starts when people are in their 20s.
• Congenital muscular dystrophy starts at birth or shortly afterwards.
• Limb-Girdle muscular dystrophy often starts in a person’s teens or 20s.
• Facioscapulohumeral muscular dystrophy affects the muscles of the face, shoulders, and upper arms. It can affect anyone from teenagers to adults in their 40s.
• Distal muscular dystrophy affects the muscles of the arms, legs, hands, and feet. It usually comes on later in life, between ages 40 and 60.
• Oculopharyngeal muscular dystrophy starts in a person’s 40s or 50s. It causes weakness in the muscles of the face, neck, and shoulders, and droopy eyelids (ptosis), followed by difficulty swallowing (dysphagia).
• Emery-Dreifuss muscular dystrophy affects mainly boys, usually starting around age 10. People with this form often have heart problems along with muscle weakness.