QUOTE FOR WEDNESDAY:

“Chronic pain affects the lives of more than 60 million Americans—not to mention the countless people who care for them.

They span all ages. They live with countless diagnoses. Their stories number in the millions. Yet despite the enormous impact of chronic pain, too many people still feel isolated, misunderstood, dismissed, or unheard.

This Pain Awareness Month, we’re bringing together those millions of stories to create #OneVoiceForPain. Because no one with pain has to face it alone. And no one is going to create a better future for those living with pain by working alone.”

U.S. Pain Foundation (This Pain Awareness Month, Let’s Change Pain – U.S. Pain Foundation)

Pain Awareness Month: How to close gates of pain, the role of stress, consequence of chronic stress and the key to prevent it!

 

In most instances, painful sensations arise from tissue injury in the body. Sensitive nerve endings pick up pain signals and carry these messages along nerves to the spinal cord and then onto the brain. All along these complex pathways, there are biological “gates” that can be either opened or closed. When these gates are closed, pain is reduced or eliminated. When open, pain messages continue through the circuit. It is when these gates are jammed open that chronic pain cycles begin.

As you recall, acute pain is short lived and serves as a warning signal. When you fix whatever is wrong, the pain usually goes away. In the case of chronic pain, pain does not necessarily signal that the body is undergoing more damage. Most chronic pain is caused by a malfunction of the nervous system, either in nerves or the brain. The malfunction or opening of the pain gates causes and endless barrage of pain signals to cycle. Chronic pain then becomes a disease itself, taking on a life of its own.

How can we close the gates of pain?

The gates are affected by several factors, most importantly by the pattern of nerve impulses which reach the spinal cord from the rest of the body, and nerve impulses coming from the brain. Sometimes the nerve impulses traveling through the spinal gates can be affected by other forms of physical stimulation. Giving your nervous system a competing source of input can fool the nervous system and alter your perception of pain.

There are many ways to accomplish this. You may have noticed that rubbing or massaging a painful area may have relieved your pain in the past. Applying electrical stimulation (e.g. TENS), applying heat or cold, acupuncture, or nerve blocks may also provide a competing source of input. It is also important to realize that certain mental activities or thoughts taking place in the brain can help to close the spinal gates.

Another way we can work to close the gates of pain is to affect the release of several chemicals that help pain signals travel to the brain. Neurotransmitters are biochemical messengers that carry pain signals from one nerve cell to the next. The three main neurotransmitters that send pain signals to the brain are substance P, NMDA (n-methyl-d-aspartate), and glutamate. Excess amounts of these chemicals, especially substance P, make it easier for pain signals to reach the brain.

Therefore, another way of stopping pain involves manipulating pain provoking neurotransmitters. This can be accomplished by prescription or over the counter medications, acupuncture, injections, hypnosis, or biofeedback.:

The role of the Endorphins:

The endorphins are another class of chemicals which are produced in the brain and serve an important role in the pain experience. These chemical are naturally occurring pain relieving substances, similar to morphine or other opiates, produced in the body. Endorphins work on special receptor sites in the brain. They act as keys which unlock receptors thus generating nerve impulses to shut down pain. Morphine and other opiates have similar chemical structures which turn off pain.
Several situations or conditions raise endorphin levels in the brain thus reducing pain. They include thinking with a positive attitude, happiness, and regular exercise.

The Role of Stress:

It is natural to connect a physical stress to the body, such a broken arm, to the perception of pain. The role of psychological stress may not seem as obvious. The brain structures involved in stress can affect the production of key hormones in the body, suppress the body’s immune system, and activate the autonomic nervous. These are the same biological changes that may occur from physical stresses on the body-the body may not differentiate between physical and psychological stress. The net effects of these changes on the body are to lower our internal resistance to pain, thus further encouraging the chronic pain cycle.

Many sources of stress feed into the chronic pain cycle. First off, as you would expect, pain itself is stressful. Pain sensations are perceived as undesirable and are at very least annoying. Pain creates tension, both physical and emotional. Physical tension may show itself as muscle tension or affect the cardiovascular, gastrointestinal, or immune systems. Emotional tension may reveal itself as anger, frustration, worry, depression, or frustration. Both physical and emotional tension, initially set in motion by pain, worsen pain. Thus the vicious cycle of pain is begins-pain leads to tension and tension leads to more pain.

A second source of stress comes from all the negative consequences that occur as a result of a chronic pain condition. Chronic pain may create difficulties with family relationships, social or recreation activities, self-esteem, and employment.

Yet another source of stress arises from the hardships that can be encountered from the stresses of everyday living. Everything from difficulties putting on your shoes in the morning to difficulties standing long enough to go grocery shopping are added on top of pain-related stressors. In the end, an individual not only suffers from chronic pain, but from chronic stress.

The consequences of chronic stress:

Whatever the type of stress, either physical or psychological, the outcome on pain is to worsen it. Chronic stress also may result in other physical ailments such as tension headaches, muscle spasms, gastrointestinal problems, and elevated blood pressure. It can also lead to fatigue, depression, and a sense of hopelessness.

The key is how to prevent chronic pain:

Chronic pain can’t always be prevented But rememeber if you have pain go to a MD to help you get to your optimal level of function and hopes you get to PAIN FREE.

1-  ONE is staying in good physical and mental health may be the best way to prevent it or help you cope with it.
2-  Treat your health problems early.
3- Get enough sleep every night. Learn to alternate activity with rest throughout each day.
4- Exercise.
5- Eat a balanced diet.

Try to reduce stress in your life.

QUOTE FOR TUESDAY:

“In Celiac disease – The intestinal damage often causes symptoms such as diarrhea, fatigue, weight loss, bloating or anemia. It also can lead to serious complications if it is not managed or treated. In children, malabsorption can affect growth and development in addition to gastrointestinal symptoms.

There’s no definite cure for celiac disease. But for most people, following a strict gluten-free diet can help manage symptoms and help the intestines heal.

Celiac disease tends to run in families. If someone in your family has the condition, ask a member of your healthcare team if you should be tested. Also ask about testing if you or someone in your family has a risk factor for celiac disease, such as type 1 diabetes.”

MAYO CLINIC (Celiac disease – Symptoms and causes – Mayo Clinic)

Part II Celiac Disease Awareness-symptoms, problems when children have this, and treatment!

The symptoms of Celiac Disease can be:

The signs and symptoms of celiac disease can vary greatly and differ in children and adults. Digestive signs and symptoms for adults include:

  • Diarrhea
  • Fatigue
  • Weight loss
  • Bloating and gas
  • Abdominal pain
  • Nausea and vomiting
  • Constipation

However, more than half the adults with celiac disease have signs and symptoms unrelated to the digestive system, including:

  • Anemia, usually from iron deficiency
  • Loss of bone density (osteoporosis) or softening of bone (osteomalacia)
  • Itchy, blistery skin rash (dermatitis herpetiformis)
  • Mouth ulcers
  • Headaches and fatigue
  • Nervous system injury, including numbness and tingling in the feet and hands, possible problems with balance, and cognitive impairment
  • Joint pain
  • Reduced functioning of the spleen (hyposplenism)

Children

Children with celiac disease are more likely than adults to have digestive problems, including:

  • Nausea and vomiting
  • Chronic diarrhea
  • Swollen belly
  • Constipation
  • Gas
  • Pale, foul-smelling stools

The inability to absorb nutrients might result in:

  • Failure to thrive for infants
  • Damage to tooth enamel
  • Weight loss
  • Anemia
  • Irritability
  • Short stature
  • Delayed puberty
  • Neurological symptoms, including attention-deficit/hyperactivity disorder (ADHD), learning disabilities, headaches, lack of muscle coordination and seizures

Some patients may have no symptoms yet but if this disease is in your family definitely get checked for it!  You get on top of it before the celiac disease gets you first!

Treatment:

There’s no cure for celiac disease — but for most people, following a strict gluten-free diet can help manage symptoms and promote intestinal healing.

Currently, the only treatment for celiac disease is lifelong adherence to a strict gluten-free diet. People living gluten-free must avoid foods with wheat, rye and barley, such as bread and beer.

Ingesting small amounts of gluten, like crumbs from a cutting board or toaster, can trigger small intestine damage.

Celiac disease is also known as coeliac disease, celiac sprue, non-tropical sprue, and gluten sensitive enteropathy.

QUOTE FOR MONDAY:

“Celiac disease (also called non-tropical sprue, celiac sprue, gluten intolerance, and gluten-sensitive enteropathy) is an intestinal disorder in which the body cannot tolerate gluten. Gluten is a natural protein in many grains, including wheat, barley, rye, and oats.

People with celiac disease have an immune reaction that is triggered by gluten. The immune reaction causes inflammation at the surface of the small intestine where it damages small structures (villi) on the surface of the intestine. It also damages smaller, hair-sized protrusions called microvilli. Healthy villi and microvilli are needed for normal digestion. When they are damaged, the intestine cannot absorb nutrients properly and you can become malnourished.

A tendency to develop celiac disease is genetic (inherited). Celiac disease is most common among people of northern European descent. Celiac disease is not always recognized because the symptoms can be mild and can be wrongly blamed upon other common intestinal issues. Celiac disease can be diagnosed at any age.”

Harvard Health Publishing (Celiac Disease (Non-Tropical Sprue) – Harvard Health)

 

Part I Celiac Disease Awareness-What this is, and long term problems!

Celiac disease, sometimes called celiac sprue or gluten-sensitive enteropathy, is an immune reaction to eating gluten, a protein found in wheat, barley and rye.

If you have celiac disease, eating gluten triggers an immune response in your small intestine. Over time, this reaction damages your small intestine’s lining and prevents it from absorbing some nutrients (malabsorption). The intestinal damage often causes diarrhea, fatigue, weight loss, bloating and anemia, and can lead to serious complications. Celiac Disease Foundation states “It is estimated to affect 1 in 100 people worldwide. Two and one-half million Americans are undiagnosed and are at risk for long-term health complications.”.

When the villi get damaged, nutrients cannot be absorbed properly into the body.

  • Intestinal villi are tiny, finger-like projections made up of cells that line the entire length of your small intestine. Your villi (villus is the singular, villi is the plural) absorb nutrients from the food you eat and then shuttle those nutrients into your bloodstream so they can travel where they’re needed.

Celiac disease is hereditary, meaning that it runs in families. People with a first-degree relative with celiac disease (parent, child, sibling) have a 1 in 10 risk of developing celiac disease.

Celiac disease can be difficult to diagnose because it affects people differently. There are more than 200 known celiac disease symptoms which may occur in the digestive system or other parts of the body. Some people develop celiac disease as a child, others as an adult. The reason for this is still unknown.

Celiac disease can develop at any age after people start eating foods or medicines that contain gluten. Left untreated, celiac disease can lead to additional serious health problems.  Some people with celiac disease have no symptoms at all, but still test positive on the celiac disease blood test. A few others may have a negative blood test, but have a positive intestinal biopsy. However, all people with celiac disease are at risk for long-term complications, whether or not they display any symptoms.

Long Term Problems that can arise from celiac disease are the following:

  • Iron deficiency anemia
  • Early onset osteoporosis or osteopenia
  • Infertility and miscarriage
  • Lactose intolerance
  • Vitamin and mineral deficiencies
  • Central and peripheral nervous system disorders
  • Pancreatic insufficiency
  • Intestinal lymphomas and other GI cancers (malignancies)
  • Gall bladder malfunction
  • Neurological manifestations, including ataxia, epileptic seizures, dementia, migraine, neuropathy, myopathy and multifocal leucoencephalopathy

QUOTE FOR THE WEEKEND:

“Gastrointestinal diseases are health conditions that affect your gastrointestinal (GI) tract. Your GI tract is the path food takes through your digestive system — from your mouth to your rectum. It also includes your liver, pancreas and gallbladder. Some digestive system diseases cause problems that go away relatively fast with treatment. Others cause problems that are more serious.”

Cleveland Clinic (Gastrointestinal Diseases: Symptoms, Treatment & Causes)

What is GERD or ACID REFLUX? Learn the symptoms, complications, risk factors, & treatments.

What is acid reflux?

A gastrointestinal (GI) disease that is caused by a valve located between the esophagus and stomach, which normally is a strong muscular ring of tissue. This valve normally opens and closes completely preventing food backing up (called reflux) in the esophagus allowing the contents to reach the throat to the mouth. With acid reflux, what happens is this valve gets over expanded frequently to the point the valve gets overstretched and no longer fits over the opening between the esophagus and the stomach with a tight fit. Due to loss of the elasticity it now is allowing leakage from the stomach with both food and fluids going up the esophagus to the throat to the mouth due to the action of reflux, during the digestion process. What happens during digestion the stomach contents with digestive fluids from the stomach (which are acidic) are refluxed, that are NOT normally in the esophagus. In conclusion, reflux sends stomach contents that’s returning (an acidic environment) upward in the esophagus which is now in an environment not use to being exposed to the digestive fluids=acidity, which are needed to perform the digestion process of our foods/fluids that are in the stomach only. This leakage of the valve is the cause of this problem occurring=GERD or GASTROINTESTINAL REFLUX.

When you don’t have GERD food and fluids, the nutrients we swallow goes down the esophagus to the valve where it opens letting the contents into the stomach.  Than digestion takes place in about 1-2 hours after eating with no feeling of heartburn or foods or fluids we ate don’t come back up in our throat to the mouth. Normally the valve is tight enough in preventing reflux=no leakage going back up to the mouth with food and acid during digestion (the primary purpose of its function).  This means during digestion the food gets into the stomach which is broken down into smaller particles by the digestive acid fluids allowing the nutrients to pass into the bloodstream with the waste products staying in the stomach to reach the rectum.  So when stomach digestion is complete it passes all the waste products onto the smaller intestines to the larger intestines to the rectum to be evacuated, without leakage or reflux.  With GERD this contents does go backward sending it to the mouth again.

The signs and symptoms (s/s) of GERD or acid reflux:

1-Heartburn is the classic GERD symptom. It’s best described as a burning sensation in the chest and/or discomfort in the upper belly or abdomen accompanied by a feeling of fullness.

2- Regurgitation is the involuntary return of partially digested food from the stomach into the mouth. This uncomfortable symptom is commonly caused by GERD, since the esophageal sphincter (valve) is damaged to such a severe degree that the stomach juices (acidotic) can freely reflux to the level of the throat or mouth.

3-Pain present behind the sternum (chest pain) to the upper mid abdomen (where the stomach is). If severe call your M.D. or doctor to have evaluated (especially if in the chest).

4-Chronic cough to hoarseness

5-Recurrent pneumonias

6-Bloating

7-Nausea

8-Vomiting (yellow/green)

9-Lump in the throat

10-Difficulty swallowing

11-Chronic sore throat

12-Laryngitis

13-Post nasal drip

14-Ear Aches

15-Tooth decay or gingivitis (inflammation of the gums) or bad breath this is due to the acid fluids with the foods and fluids regurgitated back to the mouth from the stomach.

Complications that are caused by GERD when left untreated:

1-Narrowing of the esophagus called esophageal stricture. This is due to damage to cells in the lower esophageal from acid exposure that leads to scarring of the tissue. The scar tissue narrows the food pathway causing difficulty to swallow called dysphagia.
2-Esophagitis – inflammation of the esophagus. This constant backwash of acid can irritate the lining of your esophagus. Over time, the inflammation can cause complications such as bleeding or breathing problems leading into the next problem. 3-Esophageal Ulcers – Due to frequent exposure to acidic fluids and foods to the esophagus the mucosa gets irritated so bad it will even erode the mucosa causing skin ulceration. The esophagus environment is not use to the stomach’s = acidic. Take the outer skin of the body, if exposed long enough to acidic chemicals the skin will burn. Same principle for the esophagus constantly exposed to the environment of the stomach’s content of acidic fluids every time digestion takes place.
4-Precancerous changes to the esophagus (Barrett’s esophagus). In Barrett’s esophagus, the color and composition of the tissue lining the lower esophagus change. These changes are associated with risk of esophageal cancer. The risk of cancer is low. Cancer is rare but can happen (adenocarcinoma of the esophagus).

Risk factors:

Conditions that increase the risk of GERD would
include: Obesity, Pregnancy, Smoking, Dry Mouth, Diabetes, Asthma, Connective Tissue Disorders like scleroderma, delayed stomach empting, Zollinger-Ellison syndrome (ZES) (This is a rare disorder characterized by one or more tumors in the pancreas, duodenum, or both. The tumors cause the stomach to make too much acid, leading to peptic ulcers in the duodenum. The tumors are sometimes cancerous and spread to other areas of the body.).

Treatment:

The key to treatment is prevention but if already diagnosed GERD than it would be maintenance. There is no one answer but start with being checked by your physician if you have any symptoms indicative of this diagnosis. Start with a getting a very good diagnostic tool ordered by your doctor called an Upper GI series (endoscopy) and when it’s done it will tell the M.D. a lot in what’s going on.

Then there is medications as a remedy, that can be useful, they are classified as proton pump inhibitors to H2 Inhibitors with more.

Another great key to the treatment is your LIFESTYLE=Diet (not eating acid foods, not eating fast), activity/exercise, your height compared to your weight (BMI or simply what you weigh) and lastly if you practice healthy vs. unhealthy habits.

If you would like to learn more about this come back tomorrow to my web page when I go further on the topic GERD (part 2) regarding the diet for the disease.

QUOTE FOR FRIDAY:

“GERD, diarrhea and colorectal cancer are examples of gastrointestinal diseases. When examined, some diseases show nothing wrong with the GI tract, but there are still symptoms. Other diseases have symptoms, and there are also visible irregularities in the GI tract. You can prevent and/or treat most gastrointestinal diseases.

GI diseases can be acute or chronic:

  • An acute GI disease is one that happens suddenly and lasts a short period of time.
  • A chronic GI disease can affect you for many months or years.

They can also be either functional or structural:

  • A functional GI disease is when your healthcare provider can’t see any physical or structural issues when they examine your digestive tract.
  • A structural GI disease is when your healthcare provider can see evidence of an issue when they examine you.”

Cleveland Clinic (Gastrointestinal Diseases: Symptoms, Treatment & Causes)

Gastrointestinal Diseases-What it is and types of common functional and structural GI diseases!

GERD, diarrhea and colorectal cancer are examples of gastrointestinal diseases. When examined, some diseases show nothing wrong with the GI tract, but there are still symptoms. Other diseases have symptoms, and there are also visible irregularities in the GI tract. Most gastrointestinal diseases can be prevented and/or treated.

What are gastrointestinal diseases?

Gastrointestinal diseases affect the gastrointestinal (GI) tract from the mouth to the anus. There are two types: functional and structural. Some examples include nausea/vomiting, food poisoning, lactose intolerance and diarrhea.

What are functional gastrointestinal diseases?

Functional diseases are those in which the GI tract looks normal when examined, but doesn’t move properly. They are the most common problems affecting the GI tract (including the colon and rectum). Constipation, irritable bowel syndrome (IBS), nausea, food poisoning, gas, bloating, GERD and diarrhea are common examples.

Many factors may upset your GI tract and its motility (ability to keep moving), including:

  • Eating a diet low in fiber.
  • Not getting enough exercise.
  • Traveling or other changes in routine.
  • Eating large amounts of dairy products.
  • Stress.
  • Resisting the urge to have a bowel movement, possibly because of hemorrhoids.
  • Overusing anti-diarrheal medications that, over time, weaken the bowel muscle movements called motility.
  • Taking antacid medicines containing calcium or aluminum.
  • Taking certain medicines (especially antidepressants, iron pills and strong pain medicines such as narcotics).
  • Pregnancy.

What are structural gastrointestinal diseases?

Structural gastrointestinal diseases are those where your bowel looks abnormal upon examination and also doesn’t work properly. Sometimes, the structural abnormality needs to be removed surgically. Common examples of structural GI diseases include strictures, stenosis, hemorrhoids, diverticular disease, colon polyps, colon cancer and inflammatory bowel disease.

Constipation

Constipation, which is a functional problem, makes it hard for you to have a bowel movement (or pass stools), the stools are infrequent (less than three times a week), or incomplete. Constipation is usually caused by inadequate “roughage” or fiber in your diet, or a disruption of your regular routine or diet.

Constipation causes you to strain during a bowel movement. It may cause small, hard stools and sometimes anal problems such as fissures and hemorrhoids. Constipation is rarely the sign that you have a more serious medical condition.

You can treat your constipation by:

  • Increasing the amount of fiber and water to your diet.
  • Exercising regularly and increasing the intensity of your exercises as tolerated.
  • Moving your bowels when you have the urge (resisting the urge causes constipation).

If these treatment methods don’t work, laxatives can be added. Note that you should make sure you are up to date with your colon cancer screening. Always follow the instructions on the laxative medicine, as well as the advice of your healthcare provider.

Irritable bowel syndrome (IBS)

Irritable bowel syndrome (also called spastic colon, irritable colon, IBS, or nervous stomach) is a functional condition where your colon muscle contracts more or less often than “normal.” Certain foods, medicines and emotional stress are some factors that can trigger IBS.

Symptoms of IBS include:

  • Abdominal pain and cramps.
  • Excess gas.
  • Bloating.
  • Change in bowel habits such as harder, looser, or more urgent stools than normal.
  • Alternating constipation and diarrhea.

Treatment includes:

  • Avoiding excessive caffeine.
  • Increasing fiber in your diet.
  • Monitoring which foods trigger your IBS (and avoiding these foods).
  • Minimizing stress or learning different ways to cope with stress.
  • Taking medicines as prescribed by your healthcare provider.
  • Avoiding dehydration, and hydrating well throughout the day.
  • Getting high quality rest/sleep.

Hemorrhoids

Hemorrhoids are dilated veins in the anal canal, structural disease. They’re swollen blood vessels that line your anal opening. They are caused by chronic excess pressure from straining during a bowel movement, persistent diarrhea, or pregnancy. There are two types of hemorrhoids: internal and external.

Internal hemorrhoids

Internal hemorrhoids are blood vessels on the inside of your anal opening. When they fall down into the anus as a result of straining, they become irritated and start to bleed. Ultimately, internal hemorrhoids can fall down enough to prolapse (sink or stick) out of the anus.

Treatment includes:

  • Improving bowel habits (such as avoiding constipation, not straining during bowel movements and moving your bowels when you have the urge).
  • Your healthcare provider using ligating bands to eliminate the vessels.
  • Your healthcare provider removing them surgically. Surgery is needed only for a small number of people with very large, painful and persistent hemorrhoids.

External hemorrhoids

External hemorrhoids are veins that lie just under the skin on the outside of the anus. Sometimes, after straining, the external hemorrhoidal veins burst and a blood clots form under the skin. This very painful condition is called a “pile.”

Treatment includes removing the clot and vein under local anesthesia and/or removing the hemorrhoid itself.

Anal fissures

Anal fissures are also a structural disease. They are splits or cracks in the lining of your anal opening. The most common cause of an anal fissure is the passage of very hard or watery stools. The crack in the anal lining exposes the underlying muscles that control the passage of stool through the anus and out of the body. An anal fissure is one of the most painful problems because the exposed muscles become irritated from exposure to stool or air, and leads to intense burning pain, bleeding, or spasm after bowel movements.

Initial treatment for anal fissures includes pain medicine, dietary fiber to reduce the occurrence of large, bulky stools and sitz baths (sitting in a few inches of warm water). If these treatments don’t relieve your pain, surgery might be needed to repair the sphincter muscle.

Perianal abscesses

Perianal abscesses, also a structural disease, can occur when the tiny anal glands that open on the inside of your anus become blocked, and the bacteria always present in these glands causes an infection. When pus develops, an abscess forms. Treatment includes draining the abscess, usually under local anesthesia in the healthcare provider’s office.

Anal fistula

An anal fistula – again, a structural disease – often follows drainage of an abscess and is an abnormal tube-like passageway from the anal canal to a hole in the skin near the opening of your anus. Body wastes traveling through your anal canal are diverted through this tiny channel and out through the skin, causing itching and irritation. Fistulas also cause drainage, pain and bleeding. They rarely heal by themselves and usually need surgery to drain the abscess and “close off” the fistula.

Check out Part II tomorrow!