QUOTE FOR MONDAY:

“Flu is a contagious respiratory illness that infect the nose, throat, and sometimes the lungs. Some people are at higher risk of developing serious complications from flu. If you are at higher risk, flu vaccination is especially important. When you get vaccinated, you reduce your risk of getting sick with flu and possibly being hospitalized or dying from flu. CDC recommends prompt flu antiviral treatment for people at higher risk of serious flu complications who have flu infection or suspected flu infection.

Here are some factors putting people at higher risk of getting the flu:

  • Adults 65 years and older
  • Children younger than 2 years old
  • People with asthma
  • People with chronic lung disease (such as chronic obstructive pulmonary disease [COPD] and cystic fibrosis)
  • People with neurologic and neurodevelopment conditions”

Center for Disease Control and Prevention – CDC (People at Increased Risk for Flu Complications | Influenza (Flu) | CDC)

How the flu can be dangerous to your health, even deadly.

As of January 2018 here is what was factual about the flu:
Flu season January 2018 was off to an early — and severe — start, with rates of hospitalizations and deaths from flu higher than what’s typical for this time of year.
December 14, 2018 by Steven Reinberg, Healthday Reporter. (HealthDay)—Flu season is getting off to a slow but steady start, a U.S. health official said that year and will it be the same at the end of 2020.

“Flu activity now is still fairly low, but as expected we have been seeing activity slowly increasing over the last few weeks,” said Alicia Budd, an epidemiologist at the U.S. Centers for Disease Control and Prevention.

“Unfortunately, we don’t have a crystal ball to know how badly we are going to fare during this flu season,” Budd said.

Peak activity can occur anytime between December and February, she said.  So we are not out of the clinch with the Flu time at its time of peak.  The most common type of flu around now is influenza A H1N1, which is accounting for about 80 percent of the flu viruses being reported, Budd said.

In addition, another A strain, H3N2, is also being seen, making up about 20 percent of the viruses reported 2019, she said.

“H3N2 is out there and was 2019, but at much lower levels than we saw 2018,” Budd said. It was that strain that made flu so severe last year, when 1 million people were hospitalized and 80,000 died.

Both of these types of flu are included in this season’s flu vaccine, as well as one or two influenza B strains. This year’s vaccine seems well matched to these strains, so it will most likely be more effective than last year’s vaccine, Budd said.

Because H1N1 is the predominant flu strain around now, she thinks the vaccine’s effectiveness could be as high as 65 percent.

It’s not too late to get vaccinated, Budd said. If you haven’t gotten a flu shot, it’s time, she said. It can take up to two weeks for your body to mount a protective immune response.

The most common type of flu around 2019 is influenza A H1N1, which is accounting for about 80 percent of the flu viruses being reported, Budd said.

Influenza A still is the most common type of flu!

But why was the flu so bad 2019 year?

During the week that ended Dec. 30 2017 (the most recent period for which data is available), 46 states reported widespread flu activity, up from 36 states the week before, according to the U.S. Centers for Disease Control and Prevention (CDC). At this time 2017 last year, just 12 states reported widespread flu activity.

What’s more, the rate of flu hospitalizations from the beginning of October to the end of December 2017 was about 14 hospitalizations per 100,000 people, according to CDC data. The rate was highest among adults ages 65 and older, at about 57 hospitalizations per 100,000 people. At the time Jan 2017, the rate of flu hospitalizations was just 5 hospitalizations per 100,000 people.

The flu is notoriously unpredictable, with the timing, severity and length of flu season varying from year to year, according to the CDC.

But the relatively harsh season 2019 the U.S. was having is likely related to the particular flu strains that are circulating, said Dr. Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security.

“The year 2019 was particularly bad because it’s dominated by the H3N2 [flu strain], which tends to be more severe and causes more severe symptoms than other strains of flu,” Adalja told Live Science. Indeed, flu seasons in which the H3N2 strain predominates tend to have higher overall flu hospitalization and death rates, according to the CDC.

Officials can’t predict what the final outcome for flu season will be this year in terms of illnesses, hospitalizations and deaths, but Adalja suspects it will be a notable one.

“I don’t know what the final tally will be in this flu season 2019, [but] I suspect it will be one of the worst ones we’ve had in recent years,” Adalja said.  Just like every year someone states it will be the worst year.

Another factor that may affect the severity of a flu season is whether the flu strains included in the yearly flu shot match the ones circulating in the public. So far this year, the circulating flu strains do appear to match the flu strains that were selected for the vaccine, according to a recent CDC report.

However, to make the flu vaccine, manufacturers typically use chicken eggs to “grow” the flu virus strains. During this process, the flu strains may acquire genetic changes that make the strains slightly different from those in circulation.

“You don’t end up with the same vaccine viruses that you started with” because of these genetic changes, Adalja said. This appears to have happened with the H3N2 component of this year’s flu vaccine, according to the CDC, and the changes may lower the effectiveness of the vaccine.

Researchers are finding that yearly flu shots are typically less effective against H3N2, compared with other strains of flu. A study published in 2016 found that, from 2004 to 2015, the flu shot was only 33 percent effective against H3N2 viruses, compared with 61 percent effective against H1N1 and 54 percent effective against influenza B viruses, which are another strain. This may be because, compared with other flu viruses, H3N2 viruses are more likely to acquire genetic changes that impact the effectiveness of the vaccine, the CDC said.

Health officials still recommend a yearly flu vaccine for everyone ages 6 months and older, because it’s still the best way to prevent flu. And studies have found that, even if a person does catch the flu, their illness is milder if they’ve been vaccinated. “Even lower levels of protection” are better than none, Adalja said.

The virus can directly cause death, Dr. Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security in Baltimore, told Live Science in 2016. This occurs when the flu virus causes such overwhelming inflammation in a person’s lungs that they die due to respiratory failure. Severe damage to the lungs makes it impossible for enough oxygen to pass through the lung tissue into the blood, leading to death. [Flu Shot Facts & Side Effects (Updated for 2017-2018)]

When someone dies directly from the flu, it happens very quickly, Adalja added.

The flu can also kill indirectly, meaning that the virus makes a person more susceptible to other health problems, and these health problems lead to death. For example, getting sick with the flu can make certain groups of people, such as older adults and people with chronic illnesses, more susceptible to bacteria that cause pneumonia, according to the Mayo Clinic. “Pneumonia is the most serious complication” of the flu and can be deadly, the Mayo Clinic says.

When a person with the flu gets pneumonia, the pneumonia is considered a secondary bacterial infection, Adalja said. (Pneumonia can be caused by either a virus or bacteria; in the case of a secondary infection after flu, it is caused by bacteria.) Death from such secondary infections usually occurs about a week or so after the person first got sick, because it takes time for the secondary infection to set in, Adalja said.

The flu can lead to death in other ways as well. People with the flu can experience “multiple organ failure” throughout their body (in order words, multiple organs stop working properly), which can be deadly, Adalja said.

The flu can also trigger other serious complications, including inflammation of the heart, brain or muscle tissues, according to the CDC. Infection can also lead to an extreme, body-wide inflammatory response known as sepsis, which can be life-threatening, the CDC says.

The 2017–2018 flu season has been particularly harsh, partially because the predominant strain of flu that’s spreading, H3N2, tends to cause more severe symptoms than other strains, Live Science reported the month of January 2018. And although the flu strains circulating this 2019 do match up with those covered in the season’s flu vaccine, an odd phenomenon may have occurred during the vaccine-making process inside chicken eggs. During that process, flu strains can acquire genetic changes, and this may have happened for the H3N2 component of the vaccine, Adalja said previously.

When we had not reached the end of February 2019 yet, we reached a point by CDC stating the following:

“Influenza activity in the United States during the 2017–2018 season began to increase in November and remained at high levels for several weeks during January–February. While influenza A(H3N2) viruses predominated through February, and were predominant overall for the season, influenza B viruses were more commonly reported starting in March, 2018. The season had high severity with unusually high levels of outpatient influenza-like illness, hospitalizations rates, and proportions of pneumonia and influenza-associated deaths.

CDC estimates that the burden of illness during the 2017–2018 season was also high with an estimated 48.8 million people getting sick with influenza, 22.7 million people going to a health care provider, 959,000 hospitalizations, and 79,400 deaths from influenza. The number of cases of influenza-associated illness that occurred last season was the highest since the 2009 H1N1 pandemic, when an estimated 60 million people were sick with influenza.

The 2017–2018 influenza season was additionally atypical in that it was severe for all ages of the population. The burden of influenza and the rates of influenza-associated hospitalization are generally higher for the very young and the very old, and while this was also true during the 2017–2018 season, rates of hospitalization in all age groups were the highest seasonal rates seen since hospital-based surveillance was expanded in 2005 to include all ages. This translated into an estimated 11.5 million cases of influenza in children, 30 million cases of influenza in working age adults (aged 18-64 years), and more than 7.3 million cases in adults aged 65 years and older.

Our estimates of hospitalizations and mortality associated with the 2017–2018 influenza season continue to demonstrate how severe influenza virus infection can be. We estimate overall, there were 959,000 hospitalizations and 79,400 deaths during the 2017–2018 season. More than 48,000 hospitalizations occurred in children (aged < 18 years); however, 70% of hospitalizations occurred in older adults aged ≥65 years. Older adults also accounted for 90% of deaths, highlighting that older adults are particularly vulnerable to severe disease with influenza virus infection. An estimated 10,300 deaths occurred among working age adults (aged 18–64 years), an age group that often has low influenza vaccination.”

CDC further states for 2024 and today the following:

  • “The week ending January 25, 2024, was the first time that the percent of deaths for influenza (1.7%) was higher than the percent of deaths for COVID-19. The percent of deaths for influenza has continued to increase and is 2.6% for the week ending February 8, 2025.
  • Eleven pediatric deaths associated with seasonal influenza virus infection were reported this week, bringing the 2024-2025 season total to 68 pediatric deaths.
  • CDC estimates that there have been at least 29 million illnesses, 370,000 hospitalizations, and 16,000 deaths from flu so far this season.
  • CDC recommends that everyone ages 6 months and older get an annual influenza (flu) vaccine.1
  • There are prescription flu antiviral drugs that can treat flu illness; those should be started as early as possible and are especially important for patients at higher risk for severe illness.2
  • Influenza viruses are among several viruses contributing to respiratory disease activity. CDC is providing updated, integrated information about COVID-19, flu, and respiratory syncytial virus (RSV) activity on a weekly basis.”

What does this all mean?  Get the Influenza Vaccine for PREVENTION of the flu and Prevention of an Epidemic rising.  Help yourself and community!

References: CDC Centers for Disease Control and Prevention & Health Day

 

QUOTE FOR THE WEEKEND:

“The three most common types of spina bifida include spina bifida occulta, meningocele, and myelomeningocele.

Each year, about 1,278 babies are born with spina bifida, or 1 in every 2,857 births.1Hispanic women have the highest rate of having a child with spina bifida compared with non-Hispanic white and non-Hispanic black women.

Data from birth defects tracking programs were used to estimate the total number of pregnancies affected by spina bifida in the United States and are estimated as follows:

  • Hispanic: 3.80 per 10,000 live births
  • Non-Hispanic black or African-American: 2.73 per 10,000 live births
  • Non-Hispanic white: 3.09 per 10,000 live births”

Center for Disease Control and Prevention – CDC (About Spina Bifida | Spina Bifida | CDC)

 

Part III Spina BIfida Awareness Month – How its diagnosed and treated!

 

How is Spina Bifida Diagnosed:

In most cases, spina bifida is diagnosed before birth (prenatal). However, some mild cases may go unnoticed until after birth (postnatal). Very mild forms of spinal bifida are found when doing tests for other conditions or may never be detected.

PRENATAL DIAGNOSED:

The most common screening methods used to look for spina bifida during pregnancy are maternal serum alpha fetoprotein (MSAFP) screening and fetal ultrasound.  A doctor can also perform an amniocentesis test.

  • Maternal serum alpha fetoprotein (MSAFP) screen.  At 16 to 18 weeks of pregnancy, a sample of the mother’s blood is taken to measure the level of a protein called alpha-fetoprotein (AFP), which is made naturally by the fetus and placenta.  During pregnancy, a small amount of AFP normally crosses the placenta and enters the mother’s bloodstream.  Abnormally high levels of AFP may indicate that the fetus has spina bifida or other neural tube defect.  This test is not specific for spina bifida and cannot definitively determine that there is a problem with the fetus.  This means that a high AFP level alone is not enough to be sure the fetus has a neural tube defect.  If a high level of AFP is detected, the doctor may request additional testing, such as an ultrasound or amniocentesis.

The second trimester MSAFP screen may be performed alone or as part of a larger, multiple-marker screen.  Multiple-marker screens can look for neural tube defects and other birth defects, including Down syndrome and other chromosomal abnormalities.  First trimester screens for chromosomal abnormalities also exist but signs of spina bifida are not evident until the second trimester when the MSAFP screening is performed.

  • Ultrasound.  A fetal ultrasound uses high-frequency sound waves to create a picture of the developing baby inside the womb.  It is highly accurate in diagnosing some birth defects during pregnancy, including spina bifida.  Fetal ultrasound can be performed during the first trimester (usually between 11-14 weeks) and the second trimester (usually at 18-22 weeks), and diagnosis is more accurate during the second trimester.
  • Amniocentesis.  In this test, a doctor removes a sample of the amniotic fluid that surrounds the fetus and tests it for protein levels that may indicate a neural tube defect and genetic disorders.

POSTNATAL DIAGNOSED:

Closed neural tube defects are often recognized at birth due to an abnormal fatty mass, tuft or clump of hair, or a small dimple or birthmark on the skin at the site of the spinal malformation.  Spina bifida occulta is usually found when x-rays are done for another reason.

In rare cases, myelomeningocele and meningocele are not diagnosed during routine prenatal tests.  The baby will be diagnosed when they are born with a bubble on their back.  Babies with myelomeningocele and closed neural tube defects may have muscle weakness in their feet, hips, and legs that result in joint deformities first noticed at birth.  Mild cases of spina bifida (occulta, closed neural tube defects) not diagnosed during prenatal testing may be detected postnatally using ultrasound or X-ray imaging to look at the spine.

Doctors may use magnetic resonance imaging (MRI) or a computed tomography (CT) scan to get a clearer view of the spinal cord and vertebrae.  To evaluate for hydrocephalus, the doctor will request a head ultrasound, CT or MRI to look for extra cerebrospinal fluid inside the brain.

HOW SPINA BIFIDA CAN BE PREVENTED, THE BEST TREATMENT TO GIVE YOUR BABY; being FOLIC ACID!

Women of childbearing age can reduce their risk of having a child with spina bifida by taking 400 micrograms (mcg) of folic acid every day pre-conception. Because it is water soluble, folic acid does not stay in the body for very long and needs to be taken every day to be effective against neural defects. Since half of all pregnancies in the United States are unplanned, folic acid must be taken whether a woman is planning a pregnancy or not. Research has shown that if all women of childbearing age took a multivitamin with the B-vitamin folic acid, the risk of neural tube defects could be reduced by up to 70%.  If you can prevent this the quality life is sure to be the best!

TREATMENTS FOR SPINA BIFIDA:

Some children with myelomeningocele and closed neural tube defects will need surgery to improve the alignment of their feet, legs, or spine.  Children with myelomeningocele usually have hydrocephalus and may require surgery to help drain fluid in the brain, such as the placement of a shunt or ETV.  Multiple surgeries may be required to replace the shunt, which may become clogged, infected, or disconnected.

Some individuals with myelomeningocele or closed neural tube defects require assistive devices for mobility such as braces, walkers, crutches, or wheelchairs.  The location of the defect on the spine often determines the type of assistive devices needed.  Children with a defect high on the spine will have little movement of the legs and will use a wheelchair for mobility.  Children with a defect lower on the spine usually have more strength in the legs.  They may be able to walk independently, or they may use crutches, leg braces, walkers, and wheelchairs depending on the activity.  Children with myelomeningocele usually have some degree of delayed mobility, so they are referred to physical therapists early on to maximize their strength and function.

Treatment for bladder and bowel dysfunction typically begins soon after birth.  Children with myelomeningocele and some closed neural tube defects have damage to the lowest spinal nerves which control typical bowel and bladder function.  Some children may be able to urinate typically, but most will need to drain their bladders with a catheter or thin tube 4-6 times a day to remain dry in between and to prevent kidney damage.  Kidneys are monitored closely so that medications or surgeries can be performed to prevent renal failure.  To prevent bowel accidents many people with myelomeningocele and closed neural type defects will use rectal medications or large volume enemas to have planned bowel movements.  Close follow-up with a spina bifida specialty clinic is recommended to develop a safe bowel and bladder program.

Treatment for progressive tethering of the spinal cord (called tethered cord syndrome) can be treated with surgery to help prevent further neurological deterioration.

 

 

 

 

 

 

 

 

 

QUOTE FOR FRIDAY:

“Symptoms range in severity. Your child may need surgery to repair the opening in their spine shortly after birth. In addition, treatment is available to help them manage symptoms throughout their lifetime.

Each year, about 1 in every 2,875 babies born in the U.S. has spina bifida. The exact cause of spina bifida isn’t known. But certain factors may increase the risk. There are ways to reduce the risk. “

MAYO CLINIC (Spina Bifida: What It Is, Causes, Symptoms & Treatment)

Part II Spina Bifida Awareness-The complications that can arise from Spina Bifida!

  SPINA BIFIDA

   

TETHERED SPINALCORD (shown above)

 

FETUS WITH HYDROCEPHALUS (shown above)

  HYDROCEPHALUS

Spina Bifida is one of the causes of Tethered Spinal Cord and Hydrocephalus.

Tethered Spinal Cord is a stretch-induced functional disorder associated with the fixation (tethering) effect of inelastic tissue on the caudal spinal cord, limiting its movement. This abnormal attachment is associated with progressive stretching and increased tension of the spinal cord as a child ages, potentially resulting in a variety of neurological and other symptoms.

Hydrocephalus is caused by either increased production of CSF or impaired circulation and absorption

Spina bifida is a birth defect that affects the spine. Here are the latest national statistics on spina bifida in the United States:

1.)Each year, about 1,400 babies are born with spina bifida, or 1 in every 2,758 births, according to the U.S. Centers for Disease Control and Prevention. The exact cause of spina bifida is unknown. There is no cure but most people with spina bifida lead long and productive lives.

2.)Who it effects the most: Hispanic women have the highest rate of having a child affected by spina bifida, when compared with non-Hispanic white and non-Hispanic black women. Data from 12 state-based birth defects tracking programs were used to estimate the total number of pregnancies affected by spina bifida compared to the total number of live births (also called the prevalence of spina bifida) for each racial/ethnic group:

  • Hispanic: 3.80 per 10,000 live births
  • Non-Hispanic black or African-American: 2.73 per 10,000 live births
  • Non-Hispanic white: 3.09 per 10,000 live births

The symptoms listed below are some of the ways in which tethered spinal cord syndrome may be exhibited in children:

  • Lesion on the lower back
  • Fatty tumor or deep dimple on the lower back
  • Skin discoloration on the lower back
  • Hairy patch on the lower back
  • Back pain, worsened by activity and relieved with rest
  • Leg pain, especially in the back of legs
  • Leg numbness or tingling
  • Changes in leg strength
  • Progressive or repeated muscle contractions
  • Bowel and bladder problems

Spina bifida consequences that may occur, know the type of the spina bifida gives an idea of how many problems the patient will have:

  • Abnormal sensation or paralysis, which mostly occurs with closed neural tube defects and myelomeningocele.  People with these conditions typically have some degree of leg and core muscle weakness and loss of feeling in the groin and feet or legs.  The sensation can be more significant on one side of the body.
  • You may see deterioration of the gait in the patient’s walking.  Typically, the lower in the spine where the condition occurs results in less weakness and loss of feeling.  The strength and feeling do not improve with age due to nerve damage.  People with these types of spina bifida may lose strength and sensation as they grow and mobility can become more difficult with age.  People with these conditions may walk independently or use some combination of leg braces, walkers, crutches, or wheelchairs.  As they age, they may require more of these supports.
  • Chiari II malformation, in which parts of the brain called the brain stem and the cerebellum (hindbrain) protrude downward into the spinal canal or neck area.  It is almost always seen on advanced imagining of the brain in people with myelomeningocele, but it rarely causes symptoms.  When it does, this condition can press on the spinal cord and cause a variety of symptoms including difficulty breathing, swallowing, and arm weakness.  Surgery is sometimes required to reduce pressure in this area.
  • Blockage of cerebrospinal fluid, causing a condition called hydrocephalus.  Hydrocephalus is the abnormal buildup of the fluid that surrounds the brain.  Most people with myelomeningocele have this condition, which is not seen in the other types of spina bifida.  This buildup can put damaging pressure on the brain.  Hydrocephalus is commonly treated by surgically implanting a shunt—a hollow tube—in the brain which allows drainage of the excess fluid into the abdomen where it is absorbed by the body.  The tube is tunneled under the skin and not very noticeable to others.  Another treatment option is an endoscopic third ventriculostomy or ETV, a procedure that creates a new path for the fluid to flow.
  • Meningitis, an infection in the meninges covering the brain.  It can sometimes be associated with shunts.  Meningitis may cause brain injury and can be life-threatening.
  • Tethered cord syndrome can occur with all forms of spina bifida, although it is very rare in individuals with spina bifida occulta.  Usually the spinal cord and nerves float freely.  A tethered cord means that there is some type of tissue attached to and pulling the cord down.  This can cause damage to the nerves and decrease feeling and strength, as well as problems with bowel and bladder control.  It is surgically treated if a person has symptoms.
  • Bowel and bladder incontinence affect most individuals with myelomeningocele and closed neural tube defects.  The nerves at the very bottom of the spine control bowel and bladder function and don’t usually work properly in people with these types of spina bifida.  Most people with myelomeningocele and some types of closed neural tube defects need a regimen or other assistance to drain their bladders periodically or to have regularly scheduled bowel movements.
  • Learning disabilities, including difficulty paying attention, understanding concepts, impaired motor skills, impaired memory, and difficulty with organization and problem solving are commonly seen in children with myelomeningocele.  People with strength lower down in their legs tend to have less difficulty than those with more leg weakness.  Evaluation for an individualized education plan is recommended for all children with myelomeningocele.
  • Other complications such as skin ulcers, low bone mineral density, impaired male fertility, obesity, and kidney failure can be seen in people with myelomeningocele and neural tube defects as they age.  Additionally, people with myelomeningocele are at risk for precocious puberty (when changes to that of an adult occur too soon), sleep apnea, and depression.

The estimated lifetime cost of care for a person with spina bifida, with caregiving costs, is $791,900.

Learn tomorrow how you can prevent Spina Bifida with much more!

 

 

QUOTE FOR THURSDAY:

“Spina bifida is a type of neural tube defect that happens when a fetus’s spine and spinal cord don’t close properly during early pregnancy.

The neural tube forms the brain and spinal cord during embryonic development. When it doesn’t close, it leaves a gap in the spine. This gap can affect the vertebrae, spinal cord and nearby nerves. In more severe cases, a fluid-filled sac may stick out through the opening.

Symptoms range in severity.”

Cleveland Clinic (Spina Bifida: What It Is, Causes, Symptoms & Treatment)

Part I Spina Bifida Monthly Awareness-What it is, the risk factors and the 4 different types!

spina3  4 

 spina4

Spina Bifida is the most common permanently disabling birth defect in the United States.

80% of these are located in the lumbar and sacral areas (lower back) of the spine.

Spina Bifida literally means “split spine.”

Spina Bifida happens when a baby is in the womb and the spinal column does not close all of the way. Every day, about 8 babies born in the United States have Spina Bifida or a similar birth defect of the brain and spine.

Spina bifida occurs during the third and fourth weeks of pregnancy when a portion of the fetal spinal cord fails to properly close. As a result, the child is born with a part of the spinal cord exposed on the back.

No one knows for sure the exact cause of spina bifida but have their ideas. Scientists believe that genetic and environmental factors act together to cause the condition.

Spina bifida is a birth defect that mainly affects the spine. Normally in the first month of pregnancy, a special set of cells forms the “neural tube.” The top of the tube becomes the brain and the remainder becomes the spinal cord and structures around it.  In spina bifida, the neural tube doesn’t close all the way and some of the bones of the spine don’t close in the back.

Often, abnormalities of the brain (such as hydrocephalus, described below) accompany abnormalities of the spine because the neural tube closes first in the middle and then closure proceeds both upward and downward—meaning that if something happens that prevents normal formation of the spine, it may also prevent normal formation of the part of the brain that is forming (closing) at the same time.

The term neural tube defect describes a group of conditions, including spina bifida, that occur when the neural tube does not close all the way.

Although doctors and researchers don’t know for sure why spina bifida occurs, they have identified a few risk factors:

  • Race. Spina bifida is more common among whites and Hispanics.
  • Sex. Girls are affected more often.
  • Family history of neural tube defects. Couples who’ve had one child with a neural tube defect have a slightly higher chance of having another baby with the same defect. That risk increases if two previous children have been affected by the condition.
  • In addition, a woman who was born with a neural tube defect, or who has a close relative with one, has a greater chance of giving birth to a child with spina bifida. However, most babies with spina bifida are born to parents with no known family history of the condition.
  • Folate deficiency. Folate (vitamin B-9) is important to the healthy development of a baby. Folate is the natural form of vitamin B-9. The synthetic form, found in supplements and fortified foods, is called folic acid. A folate deficiency increases the risk of spina bifida and other neural tube defects.
  • Some medications. Anti-seizure medications, such as valproic acid (Depakene), seem to cause neural tube defects when taken during pregnancy, perhaps because they interfere with the body’s ability to use folate and folic acid.
  • Diabetes. Women with diabetes who don’t control their blood sugar well have a higher risk of having a baby with spina bifida.
  • Obesity. Pre-pregnancy obesity is associated with an increased risk of neural tube birth defects, including spina bifida.
  • Increased body temperature. Some evidence suggests that increased body temperature (hyperthermia) in the early weeks of pregnancy may increase the risk of spina bifida. Elevating your core body temperature, due to fever or the use of saunas or hot tubs, has been associated with increased risk of spina bifida.
  • If you have known risk factors for spina bifida, talk with your doctor to determine if you need a larger dose or prescription dose of folic acid, even before a pregnancy begins.

There are 4 different types of Spina Bifida:

occulta, closed neural tube defects, meningocele, and myelomeningocele.

1-Occult Spinal Dysraphism (OSD) Infants with this have a dimple in their lower back. Because most babies with dimples do not have OSD, a doctor has to check using special tools and tests to be sure. Other signs are red marks, hyperpigmented patches on the back, tufts of hair or small lumps. In OSD, the spinal cord may not grow the right way and can cause serious problems as a child grows up. Infants who might have OSD should be seen by a doctor, who will recommend tests.

2-Spina Bifida Occulta It is often called “hidden Spina Bifida” because about 15 % of healthy people have it and do not know it. Spina Bifida Occulta usually does not cause harm, & has no visible signs.  Spinal Cord & nerves are usually fine.

Visible indications of spina bifida occulta (SBO) can sometimes be seen on the newborn’s skin above the spinal defect, including:

  • An abnormal tuft of hair
  • A collection of fat
  • A small dimple or birthmark.  Meningocele A meningocele causes part of the spinal cord to come through the spine like a sac that is pushed out. Nerve fluid is in the sac, and there is usually no nerve damage. Individuals with this condition may have minor disabilities.
  • Many people who have spina bifida occulta don’t even know it, unless the condition is discovered during an X-ray or other imaging test done for unrelated reasons. People find out they have it after having an X-ray of their back. It is considered an incidental finding because the X-Ray is normally done for other reasons. However, in a small group of people with SBO, pain and neurological symptoms may occur. Tethered cord can be an insidious complication that requires investigation by a neurosurgeon.

3-Meningomyelocele is a type of spina bifida. Spina bifida is a birth defect in which the spinal canal and the backbone don’t close before the baby is born. This type of birth defect is also called a neural tube defect.  Meningocele occurs when the bones do not close around the spinal cord and the meninges are pushed out through the opening, causing a fluid-filled sac to form. The meninges are three layers of membranes covering the spinal cord, consisting of dura mater, arachnoid mater and pia mater. In most cases, the spinal cord and the nerves themselves are normal or not severely affected. The sac is often covered by skin and may require surgery. This is the rarest type of spina bifida. 

4-Myelomeningocele (Meningomyelocele), also called Spina Bifida Cystica.  Myelomeningocele is the most severe form of spina bifida, occurring nearly once for every 1,000 live births.

Number 4 – This is the most severe form of Spina Bifida.

It happens when parts of the spinal cord and nerves  come through the open part of the spine. It causes nerve damage and other disabilities.  70 to 90% of children with this condition also have too much fluid on their brains HYDROCEPHALUS. This happens because fluid that protects the brain and spinal cord is unable to drain like it should. The fluid builds up, causing pressure and swelling. Without treatment, a person’s head grows too big, and may have brain damage. Children who do not have Spina Bifida can also have this problem, so parents need to check with a doctor. Usually, however, tissues and nerves are exposed, making the baby prone to life-threatening infections.  A portion of the spinal cord or nerves is exposed in a sac through an opening in the spine that may or may not be covered by the meninges. The opening can be closed by surgeons while the baby is in utero or shortly after the baby is born. Myelomeningocele is often called a snowflake condition because no two people with the condition are the same. Typically, the lower in the spine the opening occurs relates to less symptoms in the person. People with myelomeningocele require close follow-up with physicians throughout their childhood and lifespan to maximize their function and prevent complications such as kidney failure.

Neurological impairment is common, there is brain structure changes including:

  • Muscle weakness of the legs, sometimes involving paralysis
  • Bowel and bladder problems
  • Seizures, especially if the child requires a shunt
  • Orthopedic problems — such as deformed feet, uneven hips and a curved spine (scoliosis)Treatment for spina bifida depends on the severity of the condition.

    In general, Spina Bifida Treatment:

  1. Most people with spina bifida occulta require no treatment at all.
  2. Children with meningocele typically require surgical removal of the cyst and survive with little, if any, disability.
  3. Children with myelomeningocele, however take the longest road with treatment.  It require complex and often lifelong treatment and assistance. Almost all of them survive with appropriate treatment starting soon after birth. Their quality of life depends at least partially on the speed, efficiency, and comprehensiveness with which that treatment is provided.  A child born with myelomeningocele requires specialty care.  If the hospital the baby is in does not have newborn neuro surgery than the following is done:
  1. The child should be transferred immediately to a center where newborn surgery can be performed.
  2. Treatment with antibiotics is started as soon as the myelomeningocele is recognized; this prevents infection of the spinal cord, which can be fatal.

The operation involves closing the opening in the spinal cord and covering the cord with muscles and skin taken from either side of the back.

Remember the most common complications are tethered spinal cord and hydrocephalus, which can have very severe consequences.  This is discussed in the next couple of topics!

Updated 10/19/2021

QUOTE FOR WEDNESDAY:

Healthline states the following about Adult ADHD:

  • “Adult ADHD may manifest as difficulties with organization, relationship management, focus, restlessness, and managing emotions.
  • To receive an ADHD diagnosis as an adult, you must exhibit at least five symptoms associated with ADHD for a minimum of six months.
  • If you’re experiencing disruptive ADHD symptoms, seek professional evaluation. Solutions like therapy, stress management, and medication are available to help manage the condition.”

Healthline (Adult ADHD: 14 Signs and Symptoms)

Part II National Adult ADHD Awareness – Learn what happens after 18 y/o, how many have it, and the new oral med that is used in RX!

Though that ADHD is something that kids would outgrow.

We now know this is not true.

ADHD is neurobiological disorder that affects individuals across the lifespan.

ADHD doesn’t end at age 18. When adult ADHD goes undiagnosed, is misdiagnosed, or is not adequately treated, the effects can extend well beyond the individual.

The doctor for adults never diagnosed or miss diagnosed for ADHA will examine the consequences when this happens to adults with ADHD that can also include patients with  management that was discontinued, or care poorly managed, including increased risks related to employment and economic stability, relationships, physical and mental health, substance use, driving and injury, and involvement with the justice system.

For policymakers, these are not simply healthcare concerns. The effects of undiagnosed and inadequately treated ADHD can ripple through the workforce, families, schools, healthcare systems, public safety, and communities. They have a direct financial and social cost to their constituents and communities.

Approximately 15.5 million adults have been diagnosed with attention-deficit/hyperactivity disorder (ADHD). In early adulthood, ADHD may be associated with depression, mood or conduct disorders and substance abuse. Adults with ADHD often cope with difficulties at work and in their personal and family lives related to ADHD symptoms.  Many have inconsistent performance at work or in their careers; have difficulties with day-to-day responsibilities; experience relationship problems; and may have chronic feelings of frustration, guilt or blame.

Individuals with ADHD may also have difficulties with maintaining attention, executive function and working memory.  Recently, deficits in executive function have emerged as key factors affecting academic and career success. Executive function is the brain’s ability to prioritize and manage thoughts and actions. This ability permits individuals to consider the long-term consequences of their actions and guide their behavior across time more effectively.  Individuals who have issues with executive functioning may have difficulties completing tasks or may forget important things.

Healthline states that:
FDA Approves ‘First-in-Class’ NDSRI for ADHD in Adults and Children

A new medication to help treat attention deficit hyperactivity disorder (ADHD) will be available later this year. Otsuka Pharmaceutical has received approval from the Food and Drug Administration (FDA) for SIMTRIYO, a daily extended-relief tablet that contains the active ingredient centanafadine.

The new medication is approved for use in adults and children 6 years and older who weigh at least 44 pounds. Otsuka officials say their drug is the first norepinephrine, dopamine, serotonin reuptake inhibitor (NDSRI) to treat ADHD.

Max Wiznitzer, MD, a professor of pediatrics and neurology at Case Western Reserve University in Ohio and the co-chair of the Professional Advisory Board for the organization Children and Adults with ADHD (CHADD), said he also plans to use SIMTRIYO as a backup treatment for people who aren’t seeing benefits from current medications. Wiznitzer said he needs more evidence that SIMTRIYO is more effective than stimulant-based medications before prescribing it more often, but he is glad to have it available. “It’s good to have another alternative,” he told Healthline.  Remember its a NEW DRUG so you need time to see its effectiveness just like with Covid 19 that is why the vaccine was changed in time from the initial vaccine that was made with research done in a few years after 2020.