“There’s a reason your gallbladder sits so close to your liver, your body’s largest internal organ. Think of your liver as a factory. And your gallbladder as a warehouse next door. Your liver makes a powerful digestive juice called bile.  Bile helps break down the food you eat.  The gallbladder plays a key role in digesting food and getting energy from it.  Bile’s most important role is breaking down fats.  Your bile travels down your cystic duct into your small intestine. Then another branch of ductwork, called the pancreatic duct, joins the channel. The pancreatic duct carries enzymes from your pancreas. Think of this as 2 rivers coming together. The digestive juices from the liver and the pancreas play a clear role in digestion. So do other enzymes in the small intestine. ”

University Hospitals/The Science of Health

“Vocal cord dysfunction is the abnormal closing of the vocal cords when you breathe in or out. It’s also called laryngeal dysfunction, paradoxical vocal cord movement disorder or paradoxical vocal fold motion. Like asthma, vocal cord dysfunction can be triggered by breathing in lung irritants, having an upper respiratory infection or exercising. However, unlike asthma, vocal cord dysfunction isn’t an immune system reaction and doesn’t involve the lower airways.”

MAYO CLINIC

Symptoms of vocal damage include. Breathiness, huskiness, hoarseness, loss of vocal power, monotone, sore or tense throat, losing the voice, pitch breaks and easy vocal fatigue.

Vocal cord dysfunction or paradoxical vocal fold motion (PVFM) is an episodic condition that results when vocal cord movement is dysfunctional. We open our vocal cords when we breathe, and we close them when we speak, sing, swallow or lift heavy items. Vocal cord dysfunction describes what is occurring when our vocal cords close when we intended them to open to breathe. This incorrect vocal cord motion causes an abnormal narrowing of the voice box. The voice box narrowing leaves only a small opening for air to flow through the vocal cords, which can result in a sensation of difficulty moving air into or out of the lungs.

People who suffer PVFM episodes often have a very sensitive or reactive airway. Common triggers include:

• Acid reflux
• Exercise
• Postnasal drip or allergy to airborne particles
• Strong emotion
• Voice overuse
• Cough or fumes

Vocal cord dysfunction is sometimes misdiagnosed as asthma because the symptoms and triggers for PVFM and asthma can be similar. The difference between PVFM and asthma is that if you have asthma, medicines that open your breathing tubes (bronchodilators such as albuterol) will improve your breathing. If you have PVFM alone, the bronchodilator will likely not work.

To make it even more confusing, you may have both PVFM and asthma co-occurring.

What are the symptoms of vocal cord dysfunction?

• Throat or chest tightness
• Noisy inhalation
• Difficulty getting air “in”
• Feeling of throat closing
• Feeling of being “strangled”
• Intermittent shortness of breath
• Chronic cough
• Voice change/Inability to speak

Vocal Cord Dysfunction Treatment

Treatment for vocal cord dysfunction is often nonmedicinal and involves respiratory retraining therapy with a qualified speech-language pathologist. Therapy generally requires two to six 60-minute sessions. These sessions aim to:

• Identify and eliminate sources of chronic throat irritation.
• Identify and control triggers for PVFM episodes.
• Provide an exercise program to give patients better control over breathing, reduce the discomfort and fear that comes with being short of breath, and lessen PVFM episode frequency and duration.
• Include feedback to help the individual learn to relax the throat and keep the vocal cords apart when breathing.

“Functional diseases are those in which the GI tract looks normal when examined, but doesn’t move properly. They are the most common problems affecting the GI tract (including the colon and rectum).”.

Cleveland Clinic

Other perianal infections

Sometimes the skin glands near your anus become infected and need to be drained, like in this structural disease. Just behind the anus, abscesses can form that contain a small tuft of hair at the back of the pelvis (called a pilonidal cyst).

Sexually transmitted diseases that can affect the anus include anal warts, herpes, AIDS, chlamydia and gonorrhea.

Diverticular disease

The structural disease diverticulosis is the presence of small outpouchings (diverticula) in the muscular wall of your large intestine that form in weakened areas of the bowel. They usually occur in the sigmoid colon, the high-pressure area of the lower large intestine.

Diverticular disease is very common and occurs in 10% of people over age 40 and in 50% of people over age 60 in Western cultures. It is often caused by too little roughage (fiber) in the diet. Diverticulosis can sometimes develop/progress into diverticulitis

Complications of diverticular disease happen in about 10% of people with outpouchings. They include infection or inflammation (diverticulitis), bleeding and obstruction. Treatment of diverticulitis includes treating the constipation and sometimes antibiotics if really severe. Surgery is needed as last resort in those who have significant complications to remove the involved diseased segment of the colon.

Colon polyps and cancer

Each year, 130,000 Americans are diagnosed with colorectal cancer, the second most common form of cancer in the United States. Fortunately, with advances in early detection and treatment, colorectal cancer is one of the most curable forms of the disease. By using a variety of screening tests, it is possible to prevent, detect and treat the disease long before symptoms appear.

The importance of screening

Almost all colorectal cancers begin as polyps, benign (non-cancerous) growths in the tissues lining your colon and rectum. Cancer develops when these polyps grow and abnormal cells develop and start to invade surrounding tissue. Removal of polyps can prevent the development of colorectal cancer. Almost all precancerous polyps can be removed painlessly using a flexible lighted tube called a colonoscope. If not caught in the early stages, colorectal cancer can spread throughout the body. More advanced cancer requires more complicated surgical techniques.

Most early forms of colorectal cancer do not cause symptoms, which makes screening especially important. When symptoms do occur, the cancer might already be quite advanced. Symptoms include blood on or mixed in with the stool, a change in normal bowel habits, narrowing of the stool, abdominal pain, weight loss, or constant tiredness.

Most cases of colorectal cancer are detected in one of four ways:

• By screening people at average risk for colorectal cancer beginning at age 45.
• By screening people at higher risk for colorectal cancer (for example, those with a family history or a personal history of colon polyps or cancer).
• By investigating the bowel in patients with symptoms.
• A chance finding at a routine check-up.

Early detection is the best chance for a cure.

Colitis

There are several types of colitis, which are conditions that cause an inflammation of the bowel. These include:

• Infectious colitis.
• Ulcerative colitis (cause unknown).
• Crohn’s disease (cause unknown).
• Ischemic colitis (caused by not enough blood going to the colon).
• Radiation colitis (after radiotherapy).

Colitis causes diarrhea, rectal bleeding, abdominal cramps and urgency (frequent and immediate need to empty the bowels). Treatment depends on the diagnosis, which is made by colonoscopy and biopsy.

Prevention:

Can gastrointestinal diseases be prevented?

Many diseases of the colon and rectum can be prevented or minimized by maintaining a healthy lifestyle, practicing good bowel habits and getting screened for cancer.

A colonoscopy is recommended for average-risk patients at age 45. If you have a family history of colorectal cancer or polyps, a colonoscopy may be recommended at a younger age. Typically, a colonoscopy is recommended 10 years younger than the affected family member. (For example, if your brother was diagnosed with colorectal cancer or polyps at age 45, you should begin screening at age 35.)

If you have symptoms of colorectal cancer you should consult your healthcare provider right away. Common symptoms include:

• A change in normal bowel habits.
• Blood on or in the stool that is either bright or dark.
• Unusual abdominal or gas pains.
• Very narrow stool.
• A feeling that the bowel has not emptied completely after passing stool.
• Unexplained weight loss.
• Fatigue.
• Anemia (low blood count).

Other types of gastrointestinal diseases

There are many other gastrointestinal diseases. Some are discussed, but others are not covered here. Other functional and structural diseases include peptic ulcer disease, gastritis, gastroenteritis, celiac disease, Crohn’s disease, gallstones, fecal incontinence, lactose intolerance, Hirschsprung disease, abdominal adhesions, Barrett’s esophagus, appendicitis, indigestion (dyspepsia), intestinal pseudo-obstruction, pancreatitis, short bowel syndrome, Whipple’s disease, Zollinger-Ellison syndrome, malabsorption syndromes and hepatitis.

“Digestive Diseases. The digestive system made up of the gastrointestinal tract (GI), liver, pancreas, and gallbladder helps the body digest food. Digestion is important for breaking down food into nutrients, which your body uses for energy, growth, and cell repair. Some digestive diseases and conditions are acute, lasting only a short time, while others are chronic, or long-lasting.”

NIH National Institute of Diabetes, Digestive and Kidney Diseases

“Sudden cardiac arrest is the abrupt loss of heart function, breathing and consciousness. The condition usually results from a problem with your heart’s electrical system, which disrupts your heart’s pumping action and stops blood flow to your body.

Sudden cardiac arrest isn’t the same as a heart attack, when blood flow to a part of the heart is blocked. However, a heart attack can sometimes trigger an electrical disturbance that leads to sudden cardiac arrest.”

MAYO CLINIC

“Sarcoma is a rare cancer in adults and accounts for just 1% of all cancer diagnoses in the United States, where there will be estimated 13,130 new cases in 2020. Worldwide, the most common form of this cancer type is Kaposi’s sarcoma, which was diagnosed in an estimated 42,000 people and caused about 20,000 deaths in 2018. ”

Cancer Research Institute