“When the main artery down the front of the heart (LAD) is totally blocked or has a critical blockage, right at the beginning of the vessel, it is known as the Widow Maker. (The medical term for this is a proximal LAD lesion). No one knows exactly who came up with the term, but the reason they did is likely that if that artery is blocked right at the beginning of its course, then the whole artery after it goes down. This essentially means that the whole front wall of the heart goes down. As far as heart attacks go, this is a big one, with big consequences if not dealt with appropriately and FAST!”

Dr. Ahmed/myheart.net – an Interventional Cardiologist and Director of Structural Heart Disease at Princeton-Baptist Hospital.