“Lymphoplasmacytic lymphoma (LPL) is a low-grade (slow-growing) non-Hodgkin lymphoma. It develops from B lymphocytes (a type of white blood cell) that become abnormal and grow out of control. The abnormal cells in LPL can produce large amounts of abnormal antibodies (sometimes called ‘paraprotein’). In most cases of LPL, this is an IgM abnormal antibody. LPL with IgM detectable on blood tests is called Waldenström’s macroglobulinaemia (WM). It is named after the scientist who first described it. All types of LPL are treated in the same way.”.

Lymphoma Action (https://lymphoma-action.org.uk)