“Diabetes is a serious, long-term condition with a major impact on the lives and well-being of individuals, families, and societies worldwide. The global diabetes prevalence in 2019 is estimated to be 9.3% (463 million people), rising to 10.2% (578 million) by 2030 and 10.9% (700 million) by 2045 [1]. Population aging is also increasing dramatically throughout the world, especially in developing countries, creating pressures on the health system as well as social security services and policies. Nowadays, many people are familiar with type 1 or type 2 diabetes mellitus, however, there is another form of diabetes that has just recently been identified, known as type 3 diabetes (T3DM). This lesser-known type manifests as insulin resistance within the brain and has major potential to impact neurocognition and contributes to the etiology of Alzheimer’s disease [AD]. AD has already been identified as the sixth leading cause of death in the United States, and the fifth leading cause of mortality in people 65 and older.”

National Library of Medicine – NIH (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246646/)